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Novel Targets in a High-Altitude Pulmonary Hypertension Rat Model Based on RNA-seq and Proteomics

High-altitude pulmonary hypertension (HAPH) is a complication arising from an inability to acclimatize to high altitude and is associated with high morbidity and mortality. We aimed to analyze the effects of macitentan, selexipag, riociguat, and reoxygenation on HAPH, and to screen possible targets...

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Detalles Bibliográficos
Autores principales: Xu, Xiang, Li, Hanlu, Wei, Qingxia, Li, Xin, Shen, Yanying, Guo, Ge, Chen, Yibing, He, Kunlun, Liu, Chunlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595261/
https://www.ncbi.nlm.nih.gov/pubmed/34805208
http://dx.doi.org/10.3389/fmed.2021.742436