Geranylgeraniol Restores Zoledronic Acid-Induced Efferocytosis Inhibition in Bisphosphonate-Related Osteonecrosis of the Jaw

Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe side effect of long-term administration of bisphosphonates such as zoledronic acid (ZA), but its pathogenesis remains unclear. Impairment of the clearance of apoptotic cells (termed “efferocytosis”) by ZA may be associated with the...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Zhu, Weiwen, Xu, Rongyao, Shen, Xin, Fu, Yu, Cheng, Jie, Liu, Laikui, Jiang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595285/
https://www.ncbi.nlm.nih.gov/pubmed/34805177
http://dx.doi.org/10.3389/fcell.2021.770899

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