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Transmission of cerebral amyloid pathology by peripheral administration of misfolded Aβ aggregates.

Previous reports showed that brain Aβ amyloidosis can be induced in animal models by exogenous administration of pre-formed aggregates. To date, only intra-peritoneal and intra-venous administrations are described as effective means to peripherally accelerate brain Aβ amyloidosis by seeding. Here, w...

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Detalles Bibliográficos
Autores principales: Morales, Rodrigo, Bravo-Alegria, Javiera, Moreno-Gonzalez, Ines, Duran-Aniotz, Claudia, Gamez, Nazaret, Edwards, George, Soto, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595465/
https://www.ncbi.nlm.nih.gov/pubmed/34002023
http://dx.doi.org/10.1038/s41380-021-01150-w