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Transmission of cerebral amyloid pathology by peripheral administration of misfolded Aβ aggregates.
Previous reports showed that brain Aβ amyloidosis can be induced in animal models by exogenous administration of pre-formed aggregates. To date, only intra-peritoneal and intra-venous administrations are described as effective means to peripherally accelerate brain Aβ amyloidosis by seeding. Here, w...
Autores principales: | Morales, Rodrigo, Bravo-Alegria, Javiera, Moreno-Gonzalez, Ines, Duran-Aniotz, Claudia, Gamez, Nazaret, Edwards, George, Soto, Claudio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595465/ https://www.ncbi.nlm.nih.gov/pubmed/34002023 http://dx.doi.org/10.1038/s41380-021-01150-w |
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