Cargando…
Amplifying STING Activation by Cyclic Dinucleotide-Manganese Particles for Local and Systemic Cancer Metalloimmunotherapy
Nutritional metal ions play critical roles in many important immune processes. Hence, effective modulation of metal ions may open up new forms of immunotherapy, termed as metalloimmunotherapy. Here, we demonstrate a prototype of cancer metalloimmunotherapy using cyclic dinucleotide (CDN) stimulator...
Autores principales: | Sun, Xiaoqi, Zhang, Yu, Li, Jiaqian, Park, Kyung Soo, Han, Kai, Zhou, Xingwu, Xu, Yao, Nam, Jutaek, Xu, Jin, Shi, Xiaoyue, Wei, Lei, Lei, Yu Leo, Moon, James J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595610/ https://www.ncbi.nlm.nih.gov/pubmed/34594005 http://dx.doi.org/10.1038/s41565-021-00962-9 |
Ejemplares similares
-
Metal-Based Nanoparticles for Cancer Metalloimmunotherapy
por: Suliman, Ivan Hardianto, et al.
Publicado: (2023) -
Manganese molybdate nanodots with dual amplification of STING activation for “cycle” treatment of metalloimmunotherapy
por: Lei, Huali, et al.
Publicado: (2023) -
STING cyclic dinucleotide sensing originated in bacteria
por: Morehouse, Benjamin R., et al.
Publicado: (2020) -
STING inhibitors target the cyclic dinucleotide binding pocket
por: Hong, Ze, et al.
Publicado: (2021) -
Endosomolytic Polymersomes Increase the Activity of Cyclic Dinucleotide STING Agonists to Enhance Cancer Immunotherapy
por: Shae, Daniel, et al.
Publicado: (2019)