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Understanding the role of the CB1 toggle switch in interaction networks using molecular dynamics simulation

The cannabinoid receptor 1 (CB1) is a class A G-protein coupled receptor (GPCR) that can exert various effects on the human body through the endocannabinoid system. Understanding CB1 activation has many benefits for the medical use of cannabinoids. A previous study reported that CB1 has two notable...

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Detalles Bibliográficos
Autores principales: Ji, Sangho, Yang, Wonjin, Yu, Wookyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595625/
https://www.ncbi.nlm.nih.gov/pubmed/34785728
http://dx.doi.org/10.1038/s41598-021-01767-5