De novo identification of mammalian ciliary motility proteins using cryo-EM

Dynein-decorated doublet microtubules (DMTs) are critical components of the oscillatory molecular machine of cilia, the axoneme, and have luminal surfaces patterned periodically by microtubule inner proteins (MIPs). Here we present an atomic model of the 48-nm repeat of a mammalian DMT, derived from...

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Detalles Bibliográficos
Autores principales: Gui, Miao, Farley, Hannah, Anujan, Priyanka, Anderson, Jacob R., Maxwell, Dale W., Whitchurch, Jonathan B., Botsch, J. Josephine, Qiu, Tao, Meleppattu, Shimi, Singh, Sandeep K., Zhang, Qi, Thompson, James, Lucas, Jane S., Bingle, Colin D., Norris, Dominic P., Roy, Sudipto, Brown, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595878/
https://www.ncbi.nlm.nih.gov/pubmed/34715025
http://dx.doi.org/10.1016/j.cell.2021.10.007

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