A missense variant in SHARPIN mediates Alzheimer’s disease-specific brain damages

Established genetic risk factors for Alzheimer’s disease (AD) account for only a portion of AD heritability. The aim of this study was to identify novel associations between genetic variants and AD-specific brain atrophy. We conducted genome-wide association studies for brain magnetic resonance imag...

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Detalles Bibliográficos
Autores principales: Park, Jun Young, Lee, Dongsoo, Lee, Jang Jae, Gim, Jungsoo, Gunasekaran, Tamil Iniyan, Choi, Kyu Yeong, Kang, Sarang, Do, Ah Ra, Jo, Jinyeon, Park, Juhong, Park, Kyungtaek, Li, Donghe, Lee, Sanghun, Kim, Hoowon, Dhanasingh, Immanuel, Ghosh, Suparna, Keum, Seula, Choi, Jee Hye, Song, Gyun Jee, Sael, Lee, Rhee, Sangmyung, Lovestone, Simon, Kim, Eunae, Moon, Seung Hwan, Kim, Byeong C., Kim, SangYun, Saykin, Andrew J., Nho, Kwangsik, Lee, Sung Haeng, Farrer, Lindsay A., Jun, Gyungah R., Won, Sungho, Lee, Kun Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595886/
https://www.ncbi.nlm.nih.gov/pubmed/34785643
http://dx.doi.org/10.1038/s41398-021-01680-5

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