Severe COVID-19 is associated with hyperactivation of the alternative complement pathway

BACKGROUND: Severe coronavirus disease 2019 (COVID-19) is characterized by impaired type I interferon activity and a state of hyperinflammation leading to acute respiratory distress syndrome. The complement system has recently emerged as a key player in triggering and maintaining the inflammatory st...

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Detalles Bibliográficos
Autores principales: Boussier, Jeremy, Yatim, Nader, Marchal, Armance, Hadjadj, Jérôme, Charbit, Bruno, El Sissy, Carine, Carlier, Nicolas, Pène, Frédéric, Mouthon, Luc, Tharaux, Pierre-Louis, Bergeron, Anne, Smadja, David M., Rieux-Laucat, Frédéric, Duffy, Darragh, Kernéis, Solen, Frémeaux-Bacchi, Véronique, Terrier, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Academy of Allergy, Asthma & Immunology 2022
Materias:
Covid-19
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595971/
https://www.ncbi.nlm.nih.gov/pubmed/34800432
http://dx.doi.org/10.1016/j.jaci.2021.11.004

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