Aged Breast Extracellular Matrix Drives Mammary Epithelial Cells to an Invasive and Cancer‐Like Phenotype

Age is a major risk factor for cancer. While the importance of age related genetic alterations in cells on cancer progression is well documented, the effect of aging extracellular matrix (ECM) has been overlooked. This study shows that the aging breast ECM alone is sufficient to drive normal human m...

Descripción completa

Detalles Bibliográficos
Autores principales: Bahcecioglu, Gokhan, Yue, Xiaoshan, Howe, Erin, Guldner, Ian, Stack, M. Sharon, Nakshatri, Harikrishna, Zhang, Siyuan, Zorlutuna, Pinar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596116/
https://www.ncbi.nlm.nih.gov/pubmed/34617419
http://dx.doi.org/10.1002/advs.202100128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596116/
https://www.ncbi.nlm.nih.gov/pubmed/34617419
http://dx.doi.org/10.1002/advs.202100128

Ejemplares similares