The m(6)A Readers YTHDF1 and YTHDF2 Synergistically Control Cerebellar Parallel Fiber Growth by Regulating Local Translation of the Key Wnt5a Signaling Components in Axons

Messenger RNA m(6)A modification is shown to regulate local translation in axons. However, how the m(6)A codes in axonal mRNAs are read and decoded by the m(6)A reader proteins is still unknown. Here, it is found that the m(6)A readers YTHDF1 and YTHDF2 are both expressed in cerebellar granule cells...

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Detalles Bibliográficos
Autores principales: Yu, Jun, She, Yuanchu, Yang, Lixin, Zhuang, Mengru, Han, Peng, Liu, Jianhui, Lin, Xiaoyan, Wang, Nijia, Chen, Mengxian, Jiang, Chunxuan, Zhang, Yujia, Yuan, Yujing, Ji, Sheng‐Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596126/
https://www.ncbi.nlm.nih.gov/pubmed/34643063
http://dx.doi.org/10.1002/advs.202101329

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