Cargando…

Genetic polymorphism of the drug-metabolizing enzyme Cytochrome P4502E1 (CYP2E1) in a healthy Saudi population

OBJECTIVES: Cytochrome P450 2E1 (CYP2E1) is one of the major enzymes involved in the metabolism and detoxification of various drugs and xenobiotics. Polymorphisms in the CYP2E1 gene exhibit high inter-individual variations associated with alterations in CYP2E1 gene expression and enzyme function. Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Binmahfouz, Lenah S., Bagher, Amina M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596149/ https://www.ncbi.nlm.nih.gov/pubmed/34819796 http://dx.doi.org/10.1016/j.jsps.2021.09.013

Ejemplares similares

Genetic polymorphism analysis of cytochrome P4502E1 (CYP2E1) in a Chinese Tibetan population
por: Wang, Li, et al.
Publicado: (2017)

Evaluation of cytochrome P4502E1 polymorphisms in healthy adult Western Indians and patients with antituberculous drug-induced hepatotoxicity
por: Gogtay, Nithya J., et al.
Publicado: (2016)

Roles of Cytochrome P4502E1 Gene Polymorphisms and the Risks of Alcoholic Liver Disease: A Meta-Analysis
por: Zeng, Tao, et al.
Publicado: (2013)

Innate immunity and cell death in alcoholic liver disease: Role of cytochrome P4502E1
por: Barnes, Mark A., et al.
Publicado: (2014)

Identification of a Shared Cytochrome p4502E1 Epitope Found in Anesthetic Drug-Induced and Viral Hepatitis
por: McCarthy, Elisa K., et al.
Publicado: (2018)

Evaluation of Cytochrome P4502E1 mRNA Expression and Its Effects in Antioxidant Defenses, and Cell Toxicity in Printing Workers
por: Rodríguez-Romero, Brenda Ivonn, et al.
Publicado: (2022)

The genetic profiles of CYP1A1, CYP1A2 and CYP2E1 enzymes as susceptibility factor in xenobiotic toxicity in Turkish population
por: Arici, Merve, et al.
Publicado: (2017)

Cannabinoid receptor 1 positive allosteric modulator (GAT229) attenuates cisplatin-induced neuropathic pain in mice
por: Bagher, Amina M., et al.
Publicado: (2023)

Parthenolide Phytosomes Attenuated Gentamicin-Induced Nephrotoxicity in Rats via Activation of Sirt-1, Nrf2, OH-1, and NQO1 Axis
por: Albalawi, Rawan S., et al.
Publicado: (2023)

Assessment of commitment to healthy daily habits and diets, preventive measures, and beliefs about natural products utilization during COVID-19 pandemic in certain population in Egypt and Saudi Arabia
por: El-Malah, Afaf, et al.
Publicado: (2022)

Increased Cytochrome P4502E1 Expression and Altered Hydroxyeicosatetraenoic Acid Formation Mediate Diabetic Vascular Dysfunction: Rescue by Guanylyl-Cyclase Activation
por: Schäfer, Andreas, et al.
Publicado: (2010)

Piceatannol SNEDDS Attenuates Estradiol-Induced Endometrial Hyperplasia in Rats by Modulation of NF-κB and Nrf2/HO-1 Axes
por: Binmahfouz, Lenah S., et al.
Publicado: (2022)

Erratum for McCarthy et al., “Identification of a Shared Cytochrome p4502E1 Epitope Found in Anesthetic Drug-Induced and Viral Hepatitis”
por: McCarthy, Elisa K., et al.
Publicado: (2018)

Categorization of Cytochrome P4502D6 Activity Score by Urinary Amphetamine/Methamphetamine Ratios
por: Chaichana, Jatuporn, et al.
Publicado: (2022)

Prophylactic Administration of Nanocurcumin Abates the Incidence of Liver Toxicity Induced by an Overdose of Copper Sulfate: Role of CYP4502E1, NF-κB and Bax Expressions
por: Alhusaini, Ahlam, et al.
Publicado: (2018)

HEV-Capsid Protein Interacts With Cytochrome P4502C8 and Retinol-Binding Protein 4
por: Shen, Quan, et al.
Publicado: (2011)

Calcium-Sensing Receptors Control CYP27B1-Luciferase Expression: Transcriptional and Posttranscriptional Mechanisms
por: Huang, Alice, et al.
Publicado: (2021)

Cytochrome P2E1 (CYP2E1) Gene Polymorphism as a Potential Prognostic Biomarker in Colorectal Cancer
por: Moghadas, Ayda, et al.
Publicado: (2023)

Garcinone E Mitigates Oxidative Inflammatory Response and Protects against Experimental Autoimmune Hepatitis via Modulation of Nrf2/HO-1, NF-κB and TNF-α/JNK Axis
por: Mohamed, Gamal A., et al.
Publicado: (2022)

Ethnic differences in the prevalence of polymorphisms in CYP7A1, CYP7B1 AND CYP27A1 enzymes involved in cholesterol metabolism
por: Dias, Vera, et al.
Publicado: (2011)

Preferential expression of cytochrome CYP CYP2R1 but not CYP1B1 in human cord blood hematopoietic stem and progenitor cells
por: Xu, Shuoqi, et al.
Publicado: (2014)

Polymorphic Cytochrome P450 Enzymes (CYPs) and Their Role in Personalized Therapy
por: Preissner, Sarah C., et al.
Publicado: (2013)

Polymorphisms of drug-metabolizing enzyme CYP2E1 in Chinese Uygur population
por: Zhu, Linhao, et al.
Publicado: (2018)

Validation of an HPLC Method for the Simultaneous Quantification of Metabolic Reaction Products Catalysed by CYP2E1 Enzyme Activity: Inhibitory Effect of Cytochrome P450 Enzyme CYP2E1 by Salicylic Acid in Rat Liver Microsomes
por: Salhab, Hassan, et al.
Publicado: (2020)

Levomepromazine and clozapine induce the main human cytochrome P450 drug metabolizing enzyme CYP3A4
por: Danek, Przemysław J., et al.
Publicado: (2020)

Genetic polymorphisms of cytochrome P450-1A2 (CYP1A2) among Emiratis
por: Al-Ahmad, Mohammad M., et al.
Publicado: (2017)

CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms
por: Fernandes, Glaucia Maria M, et al.
Publicado: (2016)

Effects of Genetic Polymorphisms of Drug Transporter ABCB1 (MDR1) and Cytochrome P450 Enzymes CYP2A6, CYP2B6 on Nicotine Addiction and Smoking Cessation
por: Muderrisoglu, Ahmet, et al.
Publicado: (2020)

Alteration in the Expression of Cytochrome P450s (CYP1A1, CYP2E1, and CYP3A11) in the Liver of Mouse Induced by Microcystin-LR
por: Zhang, Bangjun, et al.
Publicado: (2015)

Cytochrome P450 2E1 (CYP2E1) regulates the response to oxidative stress and migration of breast cancer cells
por: Leung, Travis, et al.
Publicado: (2013)

Cytochrome P450 CYP2E1 Suppression Ameliorates Cerebral Ischemia Reperfusion Injury
por: Yu, Jin, et al.
Publicado: (2021)

Association of CYP2C9∗3 and CYP2C8∗3 Non-Functional Alleles with Ibuprofen-Induced Upper Gastrointestinal Toxicity in a Saudi Patient
por: Bagher, Amina M.
Publicado: (2023)

Genetic polymorphisms in warfarin and tacrolimus-related genes VKORC1, CYP2C9 and CYP3A5 in the Greek-Cypriot population
por: Hadjipanagi, Despina, et al.
Publicado: (2014)

Effect of Cytochrome b5 Content on the Activity of Polymorphic CYP1A2, 2B6, and 2E1 in Human Liver Microsomes
por: Zhang, Haifeng, et al.
Publicado: (2015)

A Comparative Genomic and Phylogenetic Investigation of the Xenobiotic Metabolism Enzymes of Cytochrome P450 in Elephants Shows Loss in CYP2E and CYP4A
por: Watanabe, Kanami, et al.
Publicado: (2023)

Site-directed deuteration of dronedarone preserves cytochrome P4502J2 activity and mitigates its cardiac adverse effects in canine arrhythmic hearts
por: Karkhanis, Aneesh V., et al.
Publicado: (2022)

Genetic polymorphisms of human cytochrome P450 CYP1A1 in an Egyptian population and tobacco-induced lung cancer
por: Ezzeldin, Nada, et al.
Publicado: (2017)

Genetic variations in the drug metabolizing enzyme, CYP2E1, among various ethnic populations of Pakistan
por: Ahmed, Sagheer, et al.
Publicado: (2020)

Study of Apolipoprotein E Polymorphism in Normal Healthy Controls from Northern India
por: Chhabra, S., et al.
Publicado: (2000)

Detection of microwave radiation of cytochrome CYP102 A1 solution during the enzyme reaction
por: Ivanov, Yu.D., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_7dvt673bmoenf6281qfnresb6k