Interleukin-6 Receptor Blockade in Treatment-Refractory MOG-IgG–Associated Disease and Neuromyelitis Optica Spectrum Disorders

BACKGROUND AND OBJECTIVES: To evaluate the long-term safety and efficacy of tocilizumab (TCZ), a humanized anti–interleukin-6 receptor antibody in myelin oligodendrocyte glycoprotein–IgG–associated disease (MOGAD) and neuromyelitis optica spectrum disorders (NMOSD). METHODS: Annualized relapse rate...

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Detalles Bibliográficos
Autores principales: Ringelstein, Marius, Ayzenberg, Ilya, Lindenblatt, Gero, Fischer, Katinka, Gahlen, Anna, Novi, Giovanni, Hayward-Könnecke, Helen, Schippling, Sven, Rommer, Paulus S., Kornek, Barbara, Zrzavy, Tobias, Biotti, Damien, Ciron, Jonathan, Audoin, Bertrand, Berthele, Achim, Giglhuber, Katrin, Zephir, Helene, Kümpfel, Tania, Berger, Robert, Röther, Joachim, Häußler, Vivien, Stellmann, Jan-Patrick, Whittam, Daniel, Jacob, Anu, Kraemer, Markus, Gueguen, Antoine, Deschamps, Romain, Bayas, Antonios, Hümmert, Martin W., Trebst, Corinna, Haarmann, Axel, Jarius, Sven, Wildemann, Brigitte, Grothe, Matthias, Siebert, Nadja, Ruprecht, Klemens, Paul, Friedemann, Collongues, Nicolas, Marignier, Romain, Levy, Michael, Karenfort, Michael, Deppe, Michael, Albrecht, Philipp, Hellwig, Kerstin, Gold, Ralf, Hartung, Hans-Peter, Meuth, Sven G., Kleiter, Ingo, Aktas, Orhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596357/
https://www.ncbi.nlm.nih.gov/pubmed/34785575
http://dx.doi.org/10.1212/NXI.0000000000001100

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