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Targeting the CCL2/CCR2 Axis in Cancer Immunotherapy: One Stone, Three Birds?
CCR2 is predominantly expressed by monocytes/macrophages with strong proinflammatory functions, prompting the development of CCR2 antagonists to dampen unwanted immune responses in inflammatory and autoimmune diseases. Paradoxically, CCR2-expressing monocytes/macrophages, particularly in tumor micro...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596464/ https://www.ncbi.nlm.nih.gov/pubmed/34804061 http://dx.doi.org/10.3389/fimmu.2021.771210 |