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Targeting the CCL2/CCR2 Axis in Cancer Immunotherapy: One Stone, Three Birds?

CCR2 is predominantly expressed by monocytes/macrophages with strong proinflammatory functions, prompting the development of CCR2 antagonists to dampen unwanted immune responses in inflammatory and autoimmune diseases. Paradoxically, CCR2-expressing monocytes/macrophages, particularly in tumor micro...

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Detalles Bibliográficos
Autores principales:	Fei, Liyang, Ren, Xiaochen, Yu, Haijia, Zhan, Yifan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596464/ https://www.ncbi.nlm.nih.gov/pubmed/34804061 http://dx.doi.org/10.3389/fimmu.2021.771210

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