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Silicon photomultiplier‐based scintillation detectors for photon‐counting CT: A feasibility study

PURPOSE: The implementation of photon‐counting detectors is widely expected to be the next breakthrough in X‐ray computed tomography (CT) instrumentation. A small number of prototype scanners equipped with direct‐conversion detectors based on room‐temperature semiconductors, such as CdTe and CdZnTe...

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Autores principales: van der Sar, Stefan J., Brunner, Stefan E., Schaart, Dennis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596580/
https://www.ncbi.nlm.nih.gov/pubmed/34169535
http://dx.doi.org/10.1002/mp.14886
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author van der Sar, Stefan J.
Brunner, Stefan E.
Schaart, Dennis R.
author_facet van der Sar, Stefan J.
Brunner, Stefan E.
Schaart, Dennis R.
author_sort van der Sar, Stefan J.
collection PubMed
description PURPOSE: The implementation of photon‐counting detectors is widely expected to be the next breakthrough in X‐ray computed tomography (CT) instrumentation. A small number of prototype scanners equipped with direct‐conversion detectors based on room‐temperature semiconductors, such as CdTe and CdZnTe (CZT), are currently installed at medical centers. Here, we investigate the feasibility of using silicon photomultiplier (SiPM)‐based scintillation detectors in photon‐counting computed tomography (PCCT) scanners, as a potential alternative to CdTe and CZT detectors. METHODS: We introduce a model that allows us to compute the expected energy resolution as well as the expected pulse shape and associated rate capability of SiPM‐based PCCT detectors. The model takes into account SiPM saturation and optical crosstalk, because these phenomena may substantially affect the performance of SiPM‐based PCCT detectors with sub‐mm pixels. We present model validation experiments using a single‐pixel detector consisting of a 0.9 × 0.9 × 1.0 mm(3) LuAP:Ce scintillation crystal coupled to a 1 × 1 mm(2) SiPM. We subsequently use the validated model to compute the expected performance of the fast scintillators LYSO:Ce, LuAP:Ce, and LaBr(3):Ce, coupled to currently available SiPMs, as well as to a more advanced SiPM prototype with improved dynamic range, for sub‐mm pixel sizes. RESULTS: The model was found to be in good agreement with the validation experiments, both with respect to energy resolution and pulse shape. It shows how saturation progressively degrades the energy resolution of detectors equipped with currently available SiPMs as the pixel size decreases. Moreover, the expected pulse duration is relatively long (~200 ns) with these SiPMs. However, when LuAP:Ce and LaBr(3):Ce are coupled to the more advanced SiPM prototype, the pulse duration improves to less than 60 ns, which is in the same order of magnitude as pulses from CdTe and CZT detectors. It follows that sufficient rate capability can be achieved with pixel sizes of 400 μm or smaller. Moreover, LaBr(3):Ce detectors can provide an energy resolution of 11.5%‐13.5% at 60 keV, comparable to CdTe and CZT detectors. CONCLUSIONS: This work provides first evidence that it may be feasible to develop SiPM‐based scintillation detectors for PCCT that can compete with CdTe and CZT detectors in terms of energy resolution and rate capability.
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spelling pubmed-85965802021-11-22 Silicon photomultiplier‐based scintillation detectors for photon‐counting CT: A feasibility study van der Sar, Stefan J. Brunner, Stefan E. Schaart, Dennis R. Med Phys SPECIAL ISSUE: 6TH INTERNATIONAL CONFERENCE ON IMAGE FORMATION IN X‐RAY COMPUTED TOMOGRAPHY PURPOSE: The implementation of photon‐counting detectors is widely expected to be the next breakthrough in X‐ray computed tomography (CT) instrumentation. A small number of prototype scanners equipped with direct‐conversion detectors based on room‐temperature semiconductors, such as CdTe and CdZnTe (CZT), are currently installed at medical centers. Here, we investigate the feasibility of using silicon photomultiplier (SiPM)‐based scintillation detectors in photon‐counting computed tomography (PCCT) scanners, as a potential alternative to CdTe and CZT detectors. METHODS: We introduce a model that allows us to compute the expected energy resolution as well as the expected pulse shape and associated rate capability of SiPM‐based PCCT detectors. The model takes into account SiPM saturation and optical crosstalk, because these phenomena may substantially affect the performance of SiPM‐based PCCT detectors with sub‐mm pixels. We present model validation experiments using a single‐pixel detector consisting of a 0.9 × 0.9 × 1.0 mm(3) LuAP:Ce scintillation crystal coupled to a 1 × 1 mm(2) SiPM. We subsequently use the validated model to compute the expected performance of the fast scintillators LYSO:Ce, LuAP:Ce, and LaBr(3):Ce, coupled to currently available SiPMs, as well as to a more advanced SiPM prototype with improved dynamic range, for sub‐mm pixel sizes. RESULTS: The model was found to be in good agreement with the validation experiments, both with respect to energy resolution and pulse shape. It shows how saturation progressively degrades the energy resolution of detectors equipped with currently available SiPMs as the pixel size decreases. Moreover, the expected pulse duration is relatively long (~200 ns) with these SiPMs. However, when LuAP:Ce and LaBr(3):Ce are coupled to the more advanced SiPM prototype, the pulse duration improves to less than 60 ns, which is in the same order of magnitude as pulses from CdTe and CZT detectors. It follows that sufficient rate capability can be achieved with pixel sizes of 400 μm or smaller. Moreover, LaBr(3):Ce detectors can provide an energy resolution of 11.5%‐13.5% at 60 keV, comparable to CdTe and CZT detectors. CONCLUSIONS: This work provides first evidence that it may be feasible to develop SiPM‐based scintillation detectors for PCCT that can compete with CdTe and CZT detectors in terms of energy resolution and rate capability. John Wiley and Sons Inc. 2021-06-25 2021-10 /pmc/articles/PMC8596580/ /pubmed/34169535 http://dx.doi.org/10.1002/mp.14886 Text en © 2021 American Association of Physicists in Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle SPECIAL ISSUE: 6TH INTERNATIONAL CONFERENCE ON IMAGE FORMATION IN X‐RAY COMPUTED TOMOGRAPHY
van der Sar, Stefan J.
Brunner, Stefan E.
Schaart, Dennis R.
Silicon photomultiplier‐based scintillation detectors for photon‐counting CT: A feasibility study
title Silicon photomultiplier‐based scintillation detectors for photon‐counting CT: A feasibility study
title_full Silicon photomultiplier‐based scintillation detectors for photon‐counting CT: A feasibility study
title_fullStr Silicon photomultiplier‐based scintillation detectors for photon‐counting CT: A feasibility study
title_full_unstemmed Silicon photomultiplier‐based scintillation detectors for photon‐counting CT: A feasibility study
title_short Silicon photomultiplier‐based scintillation detectors for photon‐counting CT: A feasibility study
title_sort silicon photomultiplier‐based scintillation detectors for photon‐counting ct: a feasibility study
topic SPECIAL ISSUE: 6TH INTERNATIONAL CONFERENCE ON IMAGE FORMATION IN X‐RAY COMPUTED TOMOGRAPHY
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596580/
https://www.ncbi.nlm.nih.gov/pubmed/34169535
http://dx.doi.org/10.1002/mp.14886
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