Maternal-Fetal Pharmacology of Drugs: A Review of Current Status of the Application of Physiologically Based Pharmacokinetic Models

Pregnancy and the postpartum period are associated with several physiological changes that can alter the pharmacokinetics (PK) and pharmacodynamics (PD) of drugs. For certain drugs, dosing changes may be required during pregnancy and postpartum to achieve drug exposures comparable to what is observe...

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Detalles Bibliográficos
Autores principales: Chaphekar, Nupur, Dodeja, Prerna, Shaik, Imam H., Caritis, Steve, Venkataramanan, Raman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596611/
https://www.ncbi.nlm.nih.gov/pubmed/34805038
http://dx.doi.org/10.3389/fped.2021.733823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596611/
https://www.ncbi.nlm.nih.gov/pubmed/34805038
http://dx.doi.org/10.3389/fped.2021.733823

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