Population pharmacokinetics and genetics of oral meltdose tacrolimus (Envarsus) in stable adult liver transplant recipients

AIMS: Meltdose tacrolimus (Envarsus) is marketed as a formulation with a more consistent exposure. Due to the narrow therapeutic window, therapeutic drug monitoring is essential to maintain adequate exposure. The primary objective of this study was to develop a population pharmacokinetic (PK) model...

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Detalles Bibliográficos
Autores principales: Martial, Lisa C., Biewenga, Maaike, Ruijter, Bastian N., Keizer, Ron, Swen, Jesse J., van Hoek, Bart, Moes, Dirk Jan A. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596620/
https://www.ncbi.nlm.nih.gov/pubmed/33786892
http://dx.doi.org/10.1111/bcp.14842

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