Validation of a perioperative population factor VIII pharmacokinetic model with a large cohort of pediatric hemophilia a patients

AIMS: Population pharmacokinetic (PK) models are increasingly applied to perform individualized dosing of factor VIII (FVIII) concentrates in haemophilia A patients. To guarantee accurate performance of a population PK model in dose individualization, validation studies are of importance. However, e...

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Detalles Bibliográficos
Autores principales: Preijers, Tim, Liesner, Ri, Hazendonk, Hendrika C. A. M., Chowdary, Pratima, Driessens, Mariëtte H. E., Hart, Dan P., Laros‐van Gorkom, Britta A. P., van der Meer, Felix J. M., Meijer, Karina, Fijnvandraat, Karin, Leebeek, Frank W. G., Mathôt, Ron A. A., Cnossen, Marjon H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596686/
https://www.ncbi.nlm.nih.gov/pubmed/33884664
http://dx.doi.org/10.1111/bcp.14864

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