Inhibitors of Human Divalent Metal Transporters DMT1 (SLC11A2) and ZIP8 (SLC39A8) from a GDB‐17 Fragment Library

Solute carrier proteins (SLCs) are membrane proteins controlling fluxes across biological membranes and represent an emerging class of drug targets. Here we searched for inhibitors of divalent metal transporters in a library of 1,676 commercially available 3D‐shaped fragment‐like molecules from the...

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Detalles Bibliográficos
Autores principales: Pujol‐Giménez, Jonai, Poirier, Marion, Bühlmann, Sven, Schuppisser, Céline, Bhardwaj, Rajesh, Awale, Mahendra, Visini, Ricardo, Javor, Sacha, Hediger, Matthias A., Reymond, Jean‐Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596699/
https://www.ncbi.nlm.nih.gov/pubmed/34309203
http://dx.doi.org/10.1002/cmdc.202100467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596699/
https://www.ncbi.nlm.nih.gov/pubmed/34309203
http://dx.doi.org/10.1002/cmdc.202100467

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