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Effect of Upadacitinib on the Pharmacokinetics of Rosuvastatin or Atorvastatin in Healthy Subjects

This phase 1, 2‐part, 2‐period, open‐label, drug‐drug interaction study evaluated the potential for pharmacokinetic interactions between upadacitinib and rosuvastatin, an organic anion transporting polypeptide (OATP) 1B1 and breast cancer resistance protein substrate, or atorvastatin, a cytochrome P...

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Detalles Bibliográficos
Autores principales: Mohamed, Mohamed‐Eslam F., Coppola, Sheryl, Feng, Tian, Camp, Heidi S., Kim, Elaine, Othman, Ahmed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596765/
https://www.ncbi.nlm.nih.gov/pubmed/34109764
http://dx.doi.org/10.1002/cpdd.957