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Early Divergence in Misfolding Pathways of Amyloid‐Beta Peptides

The amyloid cascade hypothesis proposes that amyloid‐beta (Aβ) aggregation is the initial triggering event in Alzheimer's disease. Here, we utilize NMR spectroscopy and monitor the structural dynamics of two variants of Aβ, Aβ40 and Aβ42, as a function of temperature. Despite having identical a...

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Detalles Bibliográficos
Autores principales:	Mamone, Salvatore, Glöggler, Stefan, Becker, Stefan, Rezaei‐Ghaleh, Nasrollah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596873/ https://www.ncbi.nlm.nih.gov/pubmed/34355840 http://dx.doi.org/10.1002/cphc.202100542

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