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SCYN: single cell CNV profiling method using dynamic programming
BACKGROUND: Copy number variation is crucial in deciphering the mechanism and cure of complex disorders and cancers. The recent advancement of scDNA sequencing technology sheds light upon addressing intratumor heterogeneity, detecting rare subclones, and reconstructing tumor evolution lineages at si...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596905/ https://www.ncbi.nlm.nih.gov/pubmed/34789142 http://dx.doi.org/10.1186/s12864-021-07941-3 |