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SCYN: single cell CNV profiling method using dynamic programming

BACKGROUND: Copy number variation is crucial in deciphering the mechanism and cure of complex disorders and cancers. The recent advancement of scDNA sequencing technology sheds light upon addressing intratumor heterogeneity, detecting rare subclones, and reconstructing tumor evolution lineages at si...

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Detalles Bibliográficos
Autores principales: Feng, Xikang, Chen, Lingxi, Qing, Yuhao, Li, Ruikang, Li, Chaohui, Li, Shuai Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596905/
https://www.ncbi.nlm.nih.gov/pubmed/34789142
http://dx.doi.org/10.1186/s12864-021-07941-3

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