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Genetic variation of staphylococcal LukAB toxin determines receptor tropism

Staphylococcus aureus have evolved into diverse lineages, known as clonal complexes (“CC”), which exhibit differences in the coding sequences of core virulence factors. Whether these alterations impact functionality is poorly understood. Here, we studied the highly polymorphic pore-forming toxin Luk...

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Detalles Bibliográficos
Autores principales:	Perelman, Sofya S., James, David B.A., Boguslawski, Kristina M., Nelson, Chase W., Ilmain, Juliana K., Zwack, Erin E., Prescott, Rachel A., Mohamed, Adil, Tam, Kayan, Chan, Rita, Narechania, Apurva, Pawline, Miranda B., Vozhilla, Nikollaq, Moustafa, Ahmed M., Kim, Sang Y., Dittmann, Meike, Ekiert, Damian C., Bhabha, Gira, Shopsin, Bo, Planet, Paul J., Koralov, Sergei B., Torres, Victor J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597016/ https://www.ncbi.nlm.nih.gov/pubmed/33875847 http://dx.doi.org/10.1038/s41564-021-00890-3

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