Single‐Cell Transcriptomic Analysis Reveals a Hepatic Stellate Cell–Activation Roadmap and Myofibroblast Origin During Liver Fibrosis in Mice

BACKGROUND AND AIMS: HSCs and portal fibroblasts (PFs) are the major sources of collagen‐producing myofibroblasts during liver fibrosis, depending on different etiologies. However, the mechanisms by which their dynamic gene expression directs the transition from the quiescent to the activated state—...

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Detalles Bibliográficos
Autores principales: Yang, Wu, He, Hao, Wang, Tongtong, Su, Nan, Zhang, Feng, Jiang, Kai, Zhu, Jing, Zhang, Chonghe, Niu, Kongyan, Wang, Luyue, Yuan, Xiaodong, Liu, Nan, Li, Lingjie, Wei, Wu, Hu, Junhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597108/
https://www.ncbi.nlm.nih.gov/pubmed/34089528
http://dx.doi.org/10.1002/hep.31987

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