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Location‐Dependent Lanthanide Selectivity Engineered into Structurally Characterized Designed Coiled Coils

Herein we report unprecedented location‐dependent, size‐selective binding to designed lanthanide (Ln(3+)) sites within miniature protein coiled coil scaffolds. Not only do these engineered sites display unusual Ln(3+) selectivity for moderately large Ln(3+) ions (Nd to Tb), for the first time we dem...

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Detalles Bibliográficos
Autores principales: Slope, Louise N., Daubney, Oliver J., Campbell, Hannah, White, Scott A., Peacock, Anna F. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597134/
https://www.ncbi.nlm.nih.gov/pubmed/34495573
http://dx.doi.org/10.1002/anie.202110500

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