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Suicidality risk among adults with binge‐eating disorder

OBJECTIVE: To estimate relative suicidality risk associated with binge‐eating disorder (BED). METHODS: Retrospective study of patients identified as having BED (N = 1042) and a matched general population cohort (N = 10,420) from the Optum electronic health record database between January 2009 and Se...

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Autores principales: Bulik, Cynthia M., Bertoia, Monica L., Lu, Mei, Seeger, John D., Spalding, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597150/
https://www.ncbi.nlm.nih.gov/pubmed/34080227
http://dx.doi.org/10.1111/sltb.12768
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author Bulik, Cynthia M.
Bertoia, Monica L.
Lu, Mei
Seeger, John D.
Spalding, William M.
author_facet Bulik, Cynthia M.
Bertoia, Monica L.
Lu, Mei
Seeger, John D.
Spalding, William M.
author_sort Bulik, Cynthia M.
collection PubMed
description OBJECTIVE: To estimate relative suicidality risk associated with binge‐eating disorder (BED). METHODS: Retrospective study of patients identified as having BED (N = 1042) and a matched general population cohort (N = 10,420) from the Optum electronic health record database between January 2009 and September 2015. Patients had ≥1 outpatient encounter with a provider who recognized BED during the 12‐month baseline preceding entry date. Incidence and relative risk of suicidality were assessed. RESULTS: Incidence per 1000 person‐years (95% CI) of suicidal ideation and suicide attempts, respectively, was 31.1 (23.1, 41.0) and 12.7 (7.9, 19.4) in the BED cohort and 5.8 (4.7, 7.1) and 1.4 (0.9, 2.2) in the comparator cohort. Risk of suicidal ideation and suicide attempts was greater in the BED cohort (HR [95% CIs], 6.43 [4.42, 9.37]) than in the comparator cohort (HR [95% CI], 9.47 [4.99, 17.98]) during follow‐up. After adjusting for psychiatric comorbidities, associations of suicidal ideation and suicide attempts with BED remained elevated in patients with BED having histories of suicidality. CONCLUSIONS: Findings suggest that history of suicidality may result in an increased risk of suicidal ideation and suicide attempts in patients with BED relative to the general population. Psychiatric comorbidity burden may explain the elevated risk of these conditions in BED.
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spelling pubmed-85971502021-11-22 Suicidality risk among adults with binge‐eating disorder Bulik, Cynthia M. Bertoia, Monica L. Lu, Mei Seeger, John D. Spalding, William M. Suicide Life Threat Behav Original Articles OBJECTIVE: To estimate relative suicidality risk associated with binge‐eating disorder (BED). METHODS: Retrospective study of patients identified as having BED (N = 1042) and a matched general population cohort (N = 10,420) from the Optum electronic health record database between January 2009 and September 2015. Patients had ≥1 outpatient encounter with a provider who recognized BED during the 12‐month baseline preceding entry date. Incidence and relative risk of suicidality were assessed. RESULTS: Incidence per 1000 person‐years (95% CI) of suicidal ideation and suicide attempts, respectively, was 31.1 (23.1, 41.0) and 12.7 (7.9, 19.4) in the BED cohort and 5.8 (4.7, 7.1) and 1.4 (0.9, 2.2) in the comparator cohort. Risk of suicidal ideation and suicide attempts was greater in the BED cohort (HR [95% CIs], 6.43 [4.42, 9.37]) than in the comparator cohort (HR [95% CI], 9.47 [4.99, 17.98]) during follow‐up. After adjusting for psychiatric comorbidities, associations of suicidal ideation and suicide attempts with BED remained elevated in patients with BED having histories of suicidality. CONCLUSIONS: Findings suggest that history of suicidality may result in an increased risk of suicidal ideation and suicide attempts in patients with BED relative to the general population. Psychiatric comorbidity burden may explain the elevated risk of these conditions in BED. John Wiley and Sons Inc. 2021-06-03 2021-10 /pmc/articles/PMC8597150/ /pubmed/34080227 http://dx.doi.org/10.1111/sltb.12768 Text en © 2021 The Authors. Suicide and Life‐Threatening Behavior published by Wiley Periodicals LLC on behalf of American Association of Suicidology. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Bulik, Cynthia M.
Bertoia, Monica L.
Lu, Mei
Seeger, John D.
Spalding, William M.
Suicidality risk among adults with binge‐eating disorder
title Suicidality risk among adults with binge‐eating disorder
title_full Suicidality risk among adults with binge‐eating disorder
title_fullStr Suicidality risk among adults with binge‐eating disorder
title_full_unstemmed Suicidality risk among adults with binge‐eating disorder
title_short Suicidality risk among adults with binge‐eating disorder
title_sort suicidality risk among adults with binge‐eating disorder
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597150/
https://www.ncbi.nlm.nih.gov/pubmed/34080227
http://dx.doi.org/10.1111/sltb.12768
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