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Probable aerosol transmission of SARS‐CoV‐2 in a poorly ventilated courtroom

There is increasing evidence of SARS‐CoV‐2 transmission via aerosol; the number of cases of transmission via this route reported in the literature remains however limited. This study examines a case of clustering that occurred in a courtroom, in which 5 of the 10 participants were tested positive wi...

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Autores principales: Vernez, David, Schwarz, Sophie, Sauvain, Jean‐Jacques, Petignat, Christiane, Suarez, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597151/
https://www.ncbi.nlm.nih.gov/pubmed/34115411
http://dx.doi.org/10.1111/ina.12866
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author Vernez, David
Schwarz, Sophie
Sauvain, Jean‐Jacques
Petignat, Christiane
Suarez, Guillaume
author_facet Vernez, David
Schwarz, Sophie
Sauvain, Jean‐Jacques
Petignat, Christiane
Suarez, Guillaume
author_sort Vernez, David
collection PubMed
description There is increasing evidence of SARS‐CoV‐2 transmission via aerosol; the number of cases of transmission via this route reported in the literature remains however limited. This study examines a case of clustering that occurred in a courtroom, in which 5 of the 10 participants were tested positive within days of the hearing. Ventilation loss rates and dispersion of fine aerosols were measured through CO(2) injections and lactose aerosol generation. Emission rate and influencing parameters were then computed using a well‐mixed dispersion model. The emission rate from the index case was estimated at 130 quanta h(−1) (interquartile (97–155 quanta h(−1)). Measured lactose concentrations in the room were found relatively homogenous (n = 8, mean 336 µg m(−3), SD = 39 µg m(−3)). Air renewal was found to play an important role for event durations greater than 0.5 h and loss rate below 2–3 h(−1). The estimated emission rate suggests a high viral load in the index case and/or a high SARS‐CoV‐2 infection coefficient. High probabilities of infection in similar indoor situations are related to unfavorable conditions of ventilation, emission rate, and event durations. Source emission control appears essential to reduce aerosolized infection in events lasting longer than 0.5 h.
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spelling pubmed-85971512021-11-22 Probable aerosol transmission of SARS‐CoV‐2 in a poorly ventilated courtroom Vernez, David Schwarz, Sophie Sauvain, Jean‐Jacques Petignat, Christiane Suarez, Guillaume Indoor Air Original Articles There is increasing evidence of SARS‐CoV‐2 transmission via aerosol; the number of cases of transmission via this route reported in the literature remains however limited. This study examines a case of clustering that occurred in a courtroom, in which 5 of the 10 participants were tested positive within days of the hearing. Ventilation loss rates and dispersion of fine aerosols were measured through CO(2) injections and lactose aerosol generation. Emission rate and influencing parameters were then computed using a well‐mixed dispersion model. The emission rate from the index case was estimated at 130 quanta h(−1) (interquartile (97–155 quanta h(−1)). Measured lactose concentrations in the room were found relatively homogenous (n = 8, mean 336 µg m(−3), SD = 39 µg m(−3)). Air renewal was found to play an important role for event durations greater than 0.5 h and loss rate below 2–3 h(−1). The estimated emission rate suggests a high viral load in the index case and/or a high SARS‐CoV‐2 infection coefficient. High probabilities of infection in similar indoor situations are related to unfavorable conditions of ventilation, emission rate, and event durations. Source emission control appears essential to reduce aerosolized infection in events lasting longer than 0.5 h. John Wiley and Sons Inc. 2021-06-11 2021-11 /pmc/articles/PMC8597151/ /pubmed/34115411 http://dx.doi.org/10.1111/ina.12866 Text en © 2021 The Authors. Indoor Air published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Vernez, David
Schwarz, Sophie
Sauvain, Jean‐Jacques
Petignat, Christiane
Suarez, Guillaume
Probable aerosol transmission of SARS‐CoV‐2 in a poorly ventilated courtroom
title Probable aerosol transmission of SARS‐CoV‐2 in a poorly ventilated courtroom
title_full Probable aerosol transmission of SARS‐CoV‐2 in a poorly ventilated courtroom
title_fullStr Probable aerosol transmission of SARS‐CoV‐2 in a poorly ventilated courtroom
title_full_unstemmed Probable aerosol transmission of SARS‐CoV‐2 in a poorly ventilated courtroom
title_short Probable aerosol transmission of SARS‐CoV‐2 in a poorly ventilated courtroom
title_sort probable aerosol transmission of sars‐cov‐2 in a poorly ventilated courtroom
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597151/
https://www.ncbi.nlm.nih.gov/pubmed/34115411
http://dx.doi.org/10.1111/ina.12866
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