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Eculizumab Pharmacokinetics and Pharmacodynamics in Patients With Neuromyelitis Optica Spectrum Disorder

Objective: To investigate the pharmacokinetics and pharmacodynamics of the approved 900/1,200 mg dosing regimen for the terminal complement component 5 (C5) inhibitor eculizumab in patients with neuromyelitis optica spectrum disorder (NMOSD). Methods: Data were analyzed from 95 patients with aquapor...

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Detalles Bibliográficos
Autores principales:	Singh, Pratap, Gao, Xiang, Kleijn, Huub Jan, Bellanti, Francesco, Pelto, Ryan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597263/ https://www.ncbi.nlm.nih.gov/pubmed/34803867 http://dx.doi.org/10.3389/fneur.2021.696387

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