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Altered expression of fragile X mental retardation-1 (FMR1) in the thymus in autoimmune myasthenia gravis

Predisposition to autoimmunity and inflammatory disorders is observed in patients with fragile X-associated syndromes. These patients have increased numbers of CGG triplets in the 5’ UTR region of FMR1 (Fragile X Mental Retardation 1) gene, that affects its expression. FMR1 is decreased in the thymu...

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Detalles Bibliográficos
Autores principales: Thomas, Scott, Fayet, Odessa-Maud, Truffault, Frédérique, Fadel, Elie, Provost, Bastien, Hamza, Abderaouf, Berrih-Aknin, Sonia, Bonnefont, Jean-Paul, Le Panse, Rozen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597299/
https://www.ncbi.nlm.nih.gov/pubmed/34789272
http://dx.doi.org/10.1186/s12974-021-02311-y