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Evaluation of retinal functional changes after macular hole surgery using heavy brilliant blue G dye for internal limiting membrane staining: A prospective, single blind, randomized controlled trial
PURPOSE: To evaluate retinal functional changes after idiopathic macular hole (MH) surgery using heavy brilliant blue G (hBBG) dye for internal limiting membrane (ILM) staining. METHODS: Forty-four eyes with idiopathic MH were randomized into two groups – 24 eyes undergoing vitrectomy with ILM peeli...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597439/ https://www.ncbi.nlm.nih.gov/pubmed/34571629 http://dx.doi.org/10.4103/ijo.IJO_2816_20 |
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author | Kannan, Naresh Babu Chakrabarti, Anirban Sen, Sagnik Rajan, Renu P Kumar, Karthik Baliga, Girish Ramasamy, Kim |
author_facet | Kannan, Naresh Babu Chakrabarti, Anirban Sen, Sagnik Rajan, Renu P Kumar, Karthik Baliga, Girish Ramasamy, Kim |
author_sort | Kannan, Naresh Babu |
collection | PubMed |
description | PURPOSE: To evaluate retinal functional changes after idiopathic macular hole (MH) surgery using heavy brilliant blue G (hBBG) dye for internal limiting membrane (ILM) staining. METHODS: Forty-four eyes with idiopathic MH were randomized into two groups – 24 eyes undergoing vitrectomy with ILM peeling using hBBG staining and 20 eyes without staining; anatomical and functional status (with microperimetry (MP)) at baseline and during postoperative follow-up were noted and compared. RESULTS: All eyes had closure of MH postoperatively and overall baseline MP indices (average threshold, AT; foveal sensitivity, FS) improved significantly at 6 weeks and 6 months of follow-up. AT and FS showed significant improvement at 6 weeks and 6 months from baseline in both individual groups (P < 0.001). Intergroup comparison showed that there was no statistically significant difference in AT and FS values at any point of time (baseline, 6 weeks, 6 months) between staining and no-stain group. No eyes in our cohort had any unexplained visual loss. CONCLUSION: Functional parameters of macula improved significantly after successful MH surgery using hBBG for staining the ILM. |
format | Online Article Text |
id | pubmed-8597439 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-85974392021-12-07 Evaluation of retinal functional changes after macular hole surgery using heavy brilliant blue G dye for internal limiting membrane staining: A prospective, single blind, randomized controlled trial Kannan, Naresh Babu Chakrabarti, Anirban Sen, Sagnik Rajan, Renu P Kumar, Karthik Baliga, Girish Ramasamy, Kim Indian J Ophthalmol Special Focus, Retina, Original Article PURPOSE: To evaluate retinal functional changes after idiopathic macular hole (MH) surgery using heavy brilliant blue G (hBBG) dye for internal limiting membrane (ILM) staining. METHODS: Forty-four eyes with idiopathic MH were randomized into two groups – 24 eyes undergoing vitrectomy with ILM peeling using hBBG staining and 20 eyes without staining; anatomical and functional status (with microperimetry (MP)) at baseline and during postoperative follow-up were noted and compared. RESULTS: All eyes had closure of MH postoperatively and overall baseline MP indices (average threshold, AT; foveal sensitivity, FS) improved significantly at 6 weeks and 6 months of follow-up. AT and FS showed significant improvement at 6 weeks and 6 months from baseline in both individual groups (P < 0.001). Intergroup comparison showed that there was no statistically significant difference in AT and FS values at any point of time (baseline, 6 weeks, 6 months) between staining and no-stain group. No eyes in our cohort had any unexplained visual loss. CONCLUSION: Functional parameters of macula improved significantly after successful MH surgery using hBBG for staining the ILM. Wolters Kluwer - Medknow 2021-10 2021-09-25 /pmc/articles/PMC8597439/ /pubmed/34571629 http://dx.doi.org/10.4103/ijo.IJO_2816_20 Text en Copyright: © 2021 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Special Focus, Retina, Original Article Kannan, Naresh Babu Chakrabarti, Anirban Sen, Sagnik Rajan, Renu P Kumar, Karthik Baliga, Girish Ramasamy, Kim Evaluation of retinal functional changes after macular hole surgery using heavy brilliant blue G dye for internal limiting membrane staining: A prospective, single blind, randomized controlled trial |
title | Evaluation of retinal functional changes after macular hole surgery using heavy brilliant blue G dye for internal limiting membrane staining: A prospective, single blind, randomized controlled trial |
title_full | Evaluation of retinal functional changes after macular hole surgery using heavy brilliant blue G dye for internal limiting membrane staining: A prospective, single blind, randomized controlled trial |
title_fullStr | Evaluation of retinal functional changes after macular hole surgery using heavy brilliant blue G dye for internal limiting membrane staining: A prospective, single blind, randomized controlled trial |
title_full_unstemmed | Evaluation of retinal functional changes after macular hole surgery using heavy brilliant blue G dye for internal limiting membrane staining: A prospective, single blind, randomized controlled trial |
title_short | Evaluation of retinal functional changes after macular hole surgery using heavy brilliant blue G dye for internal limiting membrane staining: A prospective, single blind, randomized controlled trial |
title_sort | evaluation of retinal functional changes after macular hole surgery using heavy brilliant blue g dye for internal limiting membrane staining: a prospective, single blind, randomized controlled trial |
topic | Special Focus, Retina, Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597439/ https://www.ncbi.nlm.nih.gov/pubmed/34571629 http://dx.doi.org/10.4103/ijo.IJO_2816_20 |
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