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Identification of glaucoma from fundus images using deep learning techniques

PURPOSE: Glaucoma is one of the preeminent causes of incurable visual disability and blindness across the world due to elevated intraocular pressure within the eyes. Accurate and timely diagnosis is essential for preventing visual disability. Manual detection of glaucoma is a challenging task that n...

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Autores principales: Ajitha, S, Akkara, John D, Judy, M V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597466/
https://www.ncbi.nlm.nih.gov/pubmed/34571619
http://dx.doi.org/10.4103/ijo.IJO_92_21
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author Ajitha, S
Akkara, John D
Judy, M V
author_facet Ajitha, S
Akkara, John D
Judy, M V
author_sort Ajitha, S
collection PubMed
description PURPOSE: Glaucoma is one of the preeminent causes of incurable visual disability and blindness across the world due to elevated intraocular pressure within the eyes. Accurate and timely diagnosis is essential for preventing visual disability. Manual detection of glaucoma is a challenging task that needs expertise and years of experience. METHODS: In this paper, we suggest a powerful and accurate algorithm using a convolutional neural network (CNN) for the automatic diagnosis of glaucoma. In this work, 1113 fundus images consisting of 660 normal and 453 glaucomatous images from four databases have been used for the diagnosis of glaucoma. A 13-layer CNN is potently trained from this dataset to mine vital features, and these features are classified into either glaucomatous or normal class during testing. The proposed algorithm is implemented in Google Colab, which made the task straightforward without spending hours installing the environment and supporting libraries. To evaluate the effectiveness of our algorithm, the dataset is divided into 70% for training, 20% for validation, and the remaining 10% utilized for testing. The training images are augmented to 12012 fundus images. RESULTS: Our model with SoftMax classifier achieved an accuracy of 93.86%, sensitivity of 85.42%, specificity of 100%, and precision of 100%. In contrast, the model with the SVM classifier achieved accuracy, sensitivity, specificity, and precision of 95.61, 89.58, 100, and 100%, respectively. CONCLUSION: These results demonstrate the ability of the deep learning model to identify glaucoma from fundus images and suggest that the proposed system can help ophthalmologists in a fast, accurate, and reliable diagnosis of glaucoma.
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spelling pubmed-85974662021-12-07 Identification of glaucoma from fundus images using deep learning techniques Ajitha, S Akkara, John D Judy, M V Indian J Ophthalmol Special Focus, Glaucoma, Original Article PURPOSE: Glaucoma is one of the preeminent causes of incurable visual disability and blindness across the world due to elevated intraocular pressure within the eyes. Accurate and timely diagnosis is essential for preventing visual disability. Manual detection of glaucoma is a challenging task that needs expertise and years of experience. METHODS: In this paper, we suggest a powerful and accurate algorithm using a convolutional neural network (CNN) for the automatic diagnosis of glaucoma. In this work, 1113 fundus images consisting of 660 normal and 453 glaucomatous images from four databases have been used for the diagnosis of glaucoma. A 13-layer CNN is potently trained from this dataset to mine vital features, and these features are classified into either glaucomatous or normal class during testing. The proposed algorithm is implemented in Google Colab, which made the task straightforward without spending hours installing the environment and supporting libraries. To evaluate the effectiveness of our algorithm, the dataset is divided into 70% for training, 20% for validation, and the remaining 10% utilized for testing. The training images are augmented to 12012 fundus images. RESULTS: Our model with SoftMax classifier achieved an accuracy of 93.86%, sensitivity of 85.42%, specificity of 100%, and precision of 100%. In contrast, the model with the SVM classifier achieved accuracy, sensitivity, specificity, and precision of 95.61, 89.58, 100, and 100%, respectively. CONCLUSION: These results demonstrate the ability of the deep learning model to identify glaucoma from fundus images and suggest that the proposed system can help ophthalmologists in a fast, accurate, and reliable diagnosis of glaucoma. Wolters Kluwer - Medknow 2021-10 2021-09-25 /pmc/articles/PMC8597466/ /pubmed/34571619 http://dx.doi.org/10.4103/ijo.IJO_92_21 Text en Copyright: © 2021 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Special Focus, Glaucoma, Original Article
Ajitha, S
Akkara, John D
Judy, M V
Identification of glaucoma from fundus images using deep learning techniques
title Identification of glaucoma from fundus images using deep learning techniques
title_full Identification of glaucoma from fundus images using deep learning techniques
title_fullStr Identification of glaucoma from fundus images using deep learning techniques
title_full_unstemmed Identification of glaucoma from fundus images using deep learning techniques
title_short Identification of glaucoma from fundus images using deep learning techniques
title_sort identification of glaucoma from fundus images using deep learning techniques
topic Special Focus, Glaucoma, Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597466/
https://www.ncbi.nlm.nih.gov/pubmed/34571619
http://dx.doi.org/10.4103/ijo.IJO_92_21
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