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Total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors

PURPOSE: To evaluate the cost, safety, surgical outcome, and efficacy of modified Cutler–Beard eyelid reconstruction utilizing a novel silicone plate as a tarsal plate replacement in the repair of 60% to 100% eyelid defects following the excision of large malignant tumors. METHODS: A prospective, no...

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Autores principales: Mandal, Salil Kumar, Majumdar, Basupurna, Ganguly, Purban, Dryden, Stephen C, Fleming, James C, Fowler, Brian T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597485/
https://www.ncbi.nlm.nih.gov/pubmed/34571636
http://dx.doi.org/10.4103/ijo.IJO_2822_20
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author Mandal, Salil Kumar
Majumdar, Basupurna
Ganguly, Purban
Dryden, Stephen C
Fleming, James C
Fowler, Brian T
author_facet Mandal, Salil Kumar
Majumdar, Basupurna
Ganguly, Purban
Dryden, Stephen C
Fleming, James C
Fowler, Brian T
author_sort Mandal, Salil Kumar
collection PubMed
description PURPOSE: To evaluate the cost, safety, surgical outcome, and efficacy of modified Cutler–Beard eyelid reconstruction utilizing a novel silicone plate as a tarsal plate replacement in the repair of 60% to 100% eyelid defects following the excision of large malignant tumors. METHODS: A prospective, noncomparative, interventional study of 30 eyes was done over 3 years. Fourteen patients were female, and 16 patients were male. In all the cases, a silicone plate, the synthetic, artificial tarsal plate, was utilized for a total or subtotal replacement of the tarsal plate. The created defect was measured in mm (length and width) and later expressed in percentage. Pre- and postoperative action of levator palpebrae superioris (LPS) was measured. Pre- and postoperative measurements of the margin-to-margin reflex distance (MRD1) were noted. RESULTS: Preoperative LPS action was 1.23 ± 1.35 mm, whereas postoperative LPS actions at the end of 1 week and 18 months were 11. 8 ± 0.88 mm and 13.53 ± 0. 73 mm, respectively. Preoperative MRD1 was − 3.0 ± 1.144 mm, whereas postoperative MRD1 values at the end of 1 week and 18 months were 2.18 ± 0.27 mm and 4.16 mm ± 0.35, respectively. The mean created defect after the removal of the tumor was 87.3% ±11.10. The mean length of the silicone plate implanted in this study was 27.53 ± 2.48 mm. The follow-up period for the study participants was 18 months. CONCLUSION: The synthetic novel silicone plate was successful as a tarsal plate replacement. A second surgical site for ear cartilage harvesting is avoided. Cadaver transfer of Achilles tendon carries the risk of transmission of communicable diseases, for example, hepatitis B and HIV. Silicone is an inert, nonreacting, and tissue-tested material, thus eliminating the possibility of graft rejection. This material is readily available and cost-effective. The novel silicone plate is considered to be the most promising alternative material as a tarsal replacement in the future generation.
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spelling pubmed-85974852021-12-07 Total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors Mandal, Salil Kumar Majumdar, Basupurna Ganguly, Purban Dryden, Stephen C Fleming, James C Fowler, Brian T Indian J Ophthalmol Special Focus, Ophthalmic Plastic Surgery, Original Article PURPOSE: To evaluate the cost, safety, surgical outcome, and efficacy of modified Cutler–Beard eyelid reconstruction utilizing a novel silicone plate as a tarsal plate replacement in the repair of 60% to 100% eyelid defects following the excision of large malignant tumors. METHODS: A prospective, noncomparative, interventional study of 30 eyes was done over 3 years. Fourteen patients were female, and 16 patients were male. In all the cases, a silicone plate, the synthetic, artificial tarsal plate, was utilized for a total or subtotal replacement of the tarsal plate. The created defect was measured in mm (length and width) and later expressed in percentage. Pre- and postoperative action of levator palpebrae superioris (LPS) was measured. Pre- and postoperative measurements of the margin-to-margin reflex distance (MRD1) were noted. RESULTS: Preoperative LPS action was 1.23 ± 1.35 mm, whereas postoperative LPS actions at the end of 1 week and 18 months were 11. 8 ± 0.88 mm and 13.53 ± 0. 73 mm, respectively. Preoperative MRD1 was − 3.0 ± 1.144 mm, whereas postoperative MRD1 values at the end of 1 week and 18 months were 2.18 ± 0.27 mm and 4.16 mm ± 0.35, respectively. The mean created defect after the removal of the tumor was 87.3% ±11.10. The mean length of the silicone plate implanted in this study was 27.53 ± 2.48 mm. The follow-up period for the study participants was 18 months. CONCLUSION: The synthetic novel silicone plate was successful as a tarsal plate replacement. A second surgical site for ear cartilage harvesting is avoided. Cadaver transfer of Achilles tendon carries the risk of transmission of communicable diseases, for example, hepatitis B and HIV. Silicone is an inert, nonreacting, and tissue-tested material, thus eliminating the possibility of graft rejection. This material is readily available and cost-effective. The novel silicone plate is considered to be the most promising alternative material as a tarsal replacement in the future generation. Wolters Kluwer - Medknow 2021-10 2021-09-25 /pmc/articles/PMC8597485/ /pubmed/34571636 http://dx.doi.org/10.4103/ijo.IJO_2822_20 Text en Copyright: © 2021 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Special Focus, Ophthalmic Plastic Surgery, Original Article
Mandal, Salil Kumar
Majumdar, Basupurna
Ganguly, Purban
Dryden, Stephen C
Fleming, James C
Fowler, Brian T
Total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors
title Total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors
title_full Total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors
title_fullStr Total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors
title_full_unstemmed Total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors
title_short Total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors
title_sort total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors
topic Special Focus, Ophthalmic Plastic Surgery, Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597485/
https://www.ncbi.nlm.nih.gov/pubmed/34571636
http://dx.doi.org/10.4103/ijo.IJO_2822_20
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