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Total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors
PURPOSE: To evaluate the cost, safety, surgical outcome, and efficacy of modified Cutler–Beard eyelid reconstruction utilizing a novel silicone plate as a tarsal plate replacement in the repair of 60% to 100% eyelid defects following the excision of large malignant tumors. METHODS: A prospective, no...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597485/ https://www.ncbi.nlm.nih.gov/pubmed/34571636 http://dx.doi.org/10.4103/ijo.IJO_2822_20 |
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author | Mandal, Salil Kumar Majumdar, Basupurna Ganguly, Purban Dryden, Stephen C Fleming, James C Fowler, Brian T |
author_facet | Mandal, Salil Kumar Majumdar, Basupurna Ganguly, Purban Dryden, Stephen C Fleming, James C Fowler, Brian T |
author_sort | Mandal, Salil Kumar |
collection | PubMed |
description | PURPOSE: To evaluate the cost, safety, surgical outcome, and efficacy of modified Cutler–Beard eyelid reconstruction utilizing a novel silicone plate as a tarsal plate replacement in the repair of 60% to 100% eyelid defects following the excision of large malignant tumors. METHODS: A prospective, noncomparative, interventional study of 30 eyes was done over 3 years. Fourteen patients were female, and 16 patients were male. In all the cases, a silicone plate, the synthetic, artificial tarsal plate, was utilized for a total or subtotal replacement of the tarsal plate. The created defect was measured in mm (length and width) and later expressed in percentage. Pre- and postoperative action of levator palpebrae superioris (LPS) was measured. Pre- and postoperative measurements of the margin-to-margin reflex distance (MRD1) were noted. RESULTS: Preoperative LPS action was 1.23 ± 1.35 mm, whereas postoperative LPS actions at the end of 1 week and 18 months were 11. 8 ± 0.88 mm and 13.53 ± 0. 73 mm, respectively. Preoperative MRD1 was − 3.0 ± 1.144 mm, whereas postoperative MRD1 values at the end of 1 week and 18 months were 2.18 ± 0.27 mm and 4.16 mm ± 0.35, respectively. The mean created defect after the removal of the tumor was 87.3% ±11.10. The mean length of the silicone plate implanted in this study was 27.53 ± 2.48 mm. The follow-up period for the study participants was 18 months. CONCLUSION: The synthetic novel silicone plate was successful as a tarsal plate replacement. A second surgical site for ear cartilage harvesting is avoided. Cadaver transfer of Achilles tendon carries the risk of transmission of communicable diseases, for example, hepatitis B and HIV. Silicone is an inert, nonreacting, and tissue-tested material, thus eliminating the possibility of graft rejection. This material is readily available and cost-effective. The novel silicone plate is considered to be the most promising alternative material as a tarsal replacement in the future generation. |
format | Online Article Text |
id | pubmed-8597485 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-85974852021-12-07 Total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors Mandal, Salil Kumar Majumdar, Basupurna Ganguly, Purban Dryden, Stephen C Fleming, James C Fowler, Brian T Indian J Ophthalmol Special Focus, Ophthalmic Plastic Surgery, Original Article PURPOSE: To evaluate the cost, safety, surgical outcome, and efficacy of modified Cutler–Beard eyelid reconstruction utilizing a novel silicone plate as a tarsal plate replacement in the repair of 60% to 100% eyelid defects following the excision of large malignant tumors. METHODS: A prospective, noncomparative, interventional study of 30 eyes was done over 3 years. Fourteen patients were female, and 16 patients were male. In all the cases, a silicone plate, the synthetic, artificial tarsal plate, was utilized for a total or subtotal replacement of the tarsal plate. The created defect was measured in mm (length and width) and later expressed in percentage. Pre- and postoperative action of levator palpebrae superioris (LPS) was measured. Pre- and postoperative measurements of the margin-to-margin reflex distance (MRD1) were noted. RESULTS: Preoperative LPS action was 1.23 ± 1.35 mm, whereas postoperative LPS actions at the end of 1 week and 18 months were 11. 8 ± 0.88 mm and 13.53 ± 0. 73 mm, respectively. Preoperative MRD1 was − 3.0 ± 1.144 mm, whereas postoperative MRD1 values at the end of 1 week and 18 months were 2.18 ± 0.27 mm and 4.16 mm ± 0.35, respectively. The mean created defect after the removal of the tumor was 87.3% ±11.10. The mean length of the silicone plate implanted in this study was 27.53 ± 2.48 mm. The follow-up period for the study participants was 18 months. CONCLUSION: The synthetic novel silicone plate was successful as a tarsal plate replacement. A second surgical site for ear cartilage harvesting is avoided. Cadaver transfer of Achilles tendon carries the risk of transmission of communicable diseases, for example, hepatitis B and HIV. Silicone is an inert, nonreacting, and tissue-tested material, thus eliminating the possibility of graft rejection. This material is readily available and cost-effective. The novel silicone plate is considered to be the most promising alternative material as a tarsal replacement in the future generation. Wolters Kluwer - Medknow 2021-10 2021-09-25 /pmc/articles/PMC8597485/ /pubmed/34571636 http://dx.doi.org/10.4103/ijo.IJO_2822_20 Text en Copyright: © 2021 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Special Focus, Ophthalmic Plastic Surgery, Original Article Mandal, Salil Kumar Majumdar, Basupurna Ganguly, Purban Dryden, Stephen C Fleming, James C Fowler, Brian T Total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors |
title | Total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors |
title_full | Total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors |
title_fullStr | Total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors |
title_full_unstemmed | Total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors |
title_short | Total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors |
title_sort | total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors |
topic | Special Focus, Ophthalmic Plastic Surgery, Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597485/ https://www.ncbi.nlm.nih.gov/pubmed/34571636 http://dx.doi.org/10.4103/ijo.IJO_2822_20 |
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