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Causes of Hospitalization for Systemic Lupus Erythematosus in Saudi Arabia Compared With the Global Setting: A Retrospective Single-center Observational Study

Background: This study sought to evaluate the main causes of hospitalization of patients with systemic lupus erythematosus (SLE) in a tertiary health center in Saudi Arabia. Methods: A retrospective observational study was performed for all the SLE patients admitted to King Saud Medical City between...

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Autores principales: Alhassan, Noor, Almetri, Talal, Abualsoud, Shada, Malhis, Alaa, Al-Qahtani, Khaled, Alwazna, Abduallah, Salloum, Nourhan, Zaeri, Bandar, Hegazy, Asmaa, Mohamed, Sara, Bashawri, Yara, Al Ghanim, Nayef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597676/
https://www.ncbi.nlm.nih.gov/pubmed/34804711
http://dx.doi.org/10.7759/cureus.18858
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author Alhassan, Noor
Almetri, Talal
Abualsoud, Shada
Malhis, Alaa
Al-Qahtani, Khaled
Alwazna, Abduallah
Salloum, Nourhan
Zaeri, Bandar
Hegazy, Asmaa
Mohamed, Sara
Bashawri, Yara
Al Ghanim, Nayef
author_facet Alhassan, Noor
Almetri, Talal
Abualsoud, Shada
Malhis, Alaa
Al-Qahtani, Khaled
Alwazna, Abduallah
Salloum, Nourhan
Zaeri, Bandar
Hegazy, Asmaa
Mohamed, Sara
Bashawri, Yara
Al Ghanim, Nayef
author_sort Alhassan, Noor
collection PubMed
description Background: This study sought to evaluate the main causes of hospitalization of patients with systemic lupus erythematosus (SLE) in a tertiary health center in Saudi Arabia. Methods: A retrospective observational study was performed for all the SLE patients admitted to King Saud Medical City between 2016 and 2019. The primary reason for hospitalization was determined by the primary physician caring for the patient at the time of admission. Results: Of the 98 hospitalizations for SLE, 49% of patients were admitted from the emergency department (ED) and 51% from the rheumatology clinic. The most common reason for hospitalization was lupus flare (68.4%) followed by infection (20.4%). The lupus flare patients commonly presented with musculoskeletal (MSK)symptoms (34.6%), renal manifestations (25.5%), and skin rash (24.5%), whereas patients admitted with infection were commonly diagnosed with community-acquired pneumonia (12.2%). Other hospitalization causes were obstetric complications, adverse drug reactions, and thrombosis. Intensive care unit (ICU) admission was necessary for 7% of patients due to acute respiratory distress syndrome (ARDS) and pulmonary hemorrhage (28.6%) or other reasons (14.1%), such as pleural effusion, cardiac tamponade, and thrombotic thrombocytopenic purpura (TTP). Conclusions: The two most common reasons for SLE hospitalization were lupus flare and infection. Lupus flare was mainly due to MSK, renal, and dermatologic manifestations. The most common infection leading to hospitalization was community-acquired pneumonia, and ICU admission was mainly due to ARDS and pulmonary hemorrhage.
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spelling pubmed-85976762021-11-20 Causes of Hospitalization for Systemic Lupus Erythematosus in Saudi Arabia Compared With the Global Setting: A Retrospective Single-center Observational Study Alhassan, Noor Almetri, Talal Abualsoud, Shada Malhis, Alaa Al-Qahtani, Khaled Alwazna, Abduallah Salloum, Nourhan Zaeri, Bandar Hegazy, Asmaa Mohamed, Sara Bashawri, Yara Al Ghanim, Nayef Cureus Internal Medicine Background: This study sought to evaluate the main causes of hospitalization of patients with systemic lupus erythematosus (SLE) in a tertiary health center in Saudi Arabia. Methods: A retrospective observational study was performed for all the SLE patients admitted to King Saud Medical City between 2016 and 2019. The primary reason for hospitalization was determined by the primary physician caring for the patient at the time of admission. Results: Of the 98 hospitalizations for SLE, 49% of patients were admitted from the emergency department (ED) and 51% from the rheumatology clinic. The most common reason for hospitalization was lupus flare (68.4%) followed by infection (20.4%). The lupus flare patients commonly presented with musculoskeletal (MSK)symptoms (34.6%), renal manifestations (25.5%), and skin rash (24.5%), whereas patients admitted with infection were commonly diagnosed with community-acquired pneumonia (12.2%). Other hospitalization causes were obstetric complications, adverse drug reactions, and thrombosis. Intensive care unit (ICU) admission was necessary for 7% of patients due to acute respiratory distress syndrome (ARDS) and pulmonary hemorrhage (28.6%) or other reasons (14.1%), such as pleural effusion, cardiac tamponade, and thrombotic thrombocytopenic purpura (TTP). Conclusions: The two most common reasons for SLE hospitalization were lupus flare and infection. Lupus flare was mainly due to MSK, renal, and dermatologic manifestations. The most common infection leading to hospitalization was community-acquired pneumonia, and ICU admission was mainly due to ARDS and pulmonary hemorrhage. Cureus 2021-10-18 /pmc/articles/PMC8597676/ /pubmed/34804711 http://dx.doi.org/10.7759/cureus.18858 Text en Copyright © 2021, Alhassan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Alhassan, Noor
Almetri, Talal
Abualsoud, Shada
Malhis, Alaa
Al-Qahtani, Khaled
Alwazna, Abduallah
Salloum, Nourhan
Zaeri, Bandar
Hegazy, Asmaa
Mohamed, Sara
Bashawri, Yara
Al Ghanim, Nayef
Causes of Hospitalization for Systemic Lupus Erythematosus in Saudi Arabia Compared With the Global Setting: A Retrospective Single-center Observational Study
title Causes of Hospitalization for Systemic Lupus Erythematosus in Saudi Arabia Compared With the Global Setting: A Retrospective Single-center Observational Study
title_full Causes of Hospitalization for Systemic Lupus Erythematosus in Saudi Arabia Compared With the Global Setting: A Retrospective Single-center Observational Study
title_fullStr Causes of Hospitalization for Systemic Lupus Erythematosus in Saudi Arabia Compared With the Global Setting: A Retrospective Single-center Observational Study
title_full_unstemmed Causes of Hospitalization for Systemic Lupus Erythematosus in Saudi Arabia Compared With the Global Setting: A Retrospective Single-center Observational Study
title_short Causes of Hospitalization for Systemic Lupus Erythematosus in Saudi Arabia Compared With the Global Setting: A Retrospective Single-center Observational Study
title_sort causes of hospitalization for systemic lupus erythematosus in saudi arabia compared with the global setting: a retrospective single-center observational study
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597676/
https://www.ncbi.nlm.nih.gov/pubmed/34804711
http://dx.doi.org/10.7759/cureus.18858
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