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Impact of Deleterious Mutations on Structure, Function and Stability of Serum/Glucocorticoid Regulated Kinase 1: A Gene to Diseases Correlation

Serum and glucocorticoid-regulated kinase 1 (SGK1) is a Ser/Thr protein kinase involved in regulating cell survival, growth, proliferation, and migration. Its elevated expression and dysfunction are reported in breast, prostate, hepatocellular, lung adenoma, and renal carcinomas. We have analyzed th...

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Detalles Bibliográficos
Autores principales: AlAjmi, Mohamed F., Khan, Shama, Choudhury, Arunabh, Mohammad, Taj, Noor, Saba, Hussain, Afzal, Lu, Wenying, Eapen, Mathew Suji, Chimankar, Vrushali, Hansbro, Philip M, Sohal, Sukhwinder Singh, Elasbali, Abdelbaset Mohamed, Hassan, Md. Imtaiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597711/
https://www.ncbi.nlm.nih.gov/pubmed/34805284
http://dx.doi.org/10.3389/fmolb.2021.780284

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