Evolution of Multidrug Resistance in Plasmodium falciparum: a Longitudinal Study of Genetic Resistance Markers in the Greater Mekong Subregion

Increasing resistance in Plasmodium falciparum to artemisinins and their artemisinin combination therapy (ACT) partner drugs jeopardizes effective antimalarial treatment. Resistance is worst in the Greater Mekong subregion. Monitoring genetic markers of resistance can help to guide antimalarial ther...

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Detalles Bibliográficos
Autores principales: Imwong, Mallika, Suwannasin, Kanokon, Srisutham, Suttipat, Vongpromek, Ranitha, Promnarate, Cholrawee, Saejeng, Aungkana, Phyo, Aung Pyae, Proux, Stephane, Pongvongsa, Tiengkham, Chea, Nguon, Miotto, Olivo, Tripura, Rupam, Nguyen Hoang, Chau, Dysoley, Lek, Ho Dang Trung, Nghia, Peto, Thomas J., Callery, James J., van der Pluijm, Rob W., Amaratunga, Chanaki, Mukaka, Mavuto, von Seidlein, Lorenz, Mayxay, Mayfong, Thuy-Nhien, Nguyen Thanh, Newton, Paul N., Day, Nicholas P. J., Ashley, Elizabeth A., Nosten, Francois H., Smithuis, Frank M., Dhorda, Mehul, White, Nicholas J., Dondorp, Arjen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Epidemiology and Surveillance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597770/
https://www.ncbi.nlm.nih.gov/pubmed/34516247
http://dx.doi.org/10.1128/AAC.01121-21

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