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SARS-CoV-2 infection in free-ranging white-tailed deer (Odocoileus virginianus)
Human-to-animal spillover of SARS-CoV-2 virus has occurred in a wide range of animals, but thus far, the establishment of a new natural animal reservoir has not been detected. Here, we detected SARS-CoV-2 virus using rRT-PCR in 129 out of 360 (35.8%) free-ranging white-tailed deer (Odocoileus virgin...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597885/ https://www.ncbi.nlm.nih.gov/pubmed/34790982 http://dx.doi.org/10.1101/2021.11.04.467308 |
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author | Hale, Vanessa L. Dennis, Patricia M. McBride, Dillon S. Nolting, Jaqueline M. Madden, Christopher Huey, Devra Ehrlich, Margot Grieser, Jennifer Winston, Jenessa Lombardi, Dusty Gibson, Stormy Saif, Linda Killian, Mary L. Lantz, Kristina Tell, Rachel Torchetti, Mia Robbe-Austerman, Suelee Nelson, Martha I. Faith, Seth A. Bowman, Andrew S. |
author_facet | Hale, Vanessa L. Dennis, Patricia M. McBride, Dillon S. Nolting, Jaqueline M. Madden, Christopher Huey, Devra Ehrlich, Margot Grieser, Jennifer Winston, Jenessa Lombardi, Dusty Gibson, Stormy Saif, Linda Killian, Mary L. Lantz, Kristina Tell, Rachel Torchetti, Mia Robbe-Austerman, Suelee Nelson, Martha I. Faith, Seth A. Bowman, Andrew S. |
author_sort | Hale, Vanessa L. |
collection | PubMed |
description | Human-to-animal spillover of SARS-CoV-2 virus has occurred in a wide range of animals, but thus far, the establishment of a new natural animal reservoir has not been detected. Here, we detected SARS-CoV-2 virus using rRT-PCR in 129 out of 360 (35.8%) free-ranging white-tailed deer (Odocoileus virginianus) from northeast Ohio (USA) sampled between January-March 2021. Deer in 6 locations were infected with at least 3 lineages of SARS-CoV-2 (B.1.2, B.1.596, B.1.582). The B.1.2 viruses, dominant in Ohio at the time, spilled over multiple times into deer populations in different locations. Deer-to-deer transmission may have occurred in three locations. The establishment of a natural reservoir of SARS-CoV-2 in white-tailed deer could facilitate divergent evolutionary trajectories and future spillback to humans, further complicating long-term COVID-19 control strategies. |
format | Online Article Text |
id | pubmed-8597885 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cold Spring Harbor Laboratory |
record_format | MEDLINE/PubMed |
spelling | pubmed-85978852021-11-18 SARS-CoV-2 infection in free-ranging white-tailed deer (Odocoileus virginianus) Hale, Vanessa L. Dennis, Patricia M. McBride, Dillon S. Nolting, Jaqueline M. Madden, Christopher Huey, Devra Ehrlich, Margot Grieser, Jennifer Winston, Jenessa Lombardi, Dusty Gibson, Stormy Saif, Linda Killian, Mary L. Lantz, Kristina Tell, Rachel Torchetti, Mia Robbe-Austerman, Suelee Nelson, Martha I. Faith, Seth A. Bowman, Andrew S. bioRxiv Article Human-to-animal spillover of SARS-CoV-2 virus has occurred in a wide range of animals, but thus far, the establishment of a new natural animal reservoir has not been detected. Here, we detected SARS-CoV-2 virus using rRT-PCR in 129 out of 360 (35.8%) free-ranging white-tailed deer (Odocoileus virginianus) from northeast Ohio (USA) sampled between January-March 2021. Deer in 6 locations were infected with at least 3 lineages of SARS-CoV-2 (B.1.2, B.1.596, B.1.582). The B.1.2 viruses, dominant in Ohio at the time, spilled over multiple times into deer populations in different locations. Deer-to-deer transmission may have occurred in three locations. The establishment of a natural reservoir of SARS-CoV-2 in white-tailed deer could facilitate divergent evolutionary trajectories and future spillback to humans, further complicating long-term COVID-19 control strategies. Cold Spring Harbor Laboratory 2021-11-05 /pmc/articles/PMC8597885/ /pubmed/34790982 http://dx.doi.org/10.1101/2021.11.04.467308 Text en https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use. |
spellingShingle | Article Hale, Vanessa L. Dennis, Patricia M. McBride, Dillon S. Nolting, Jaqueline M. Madden, Christopher Huey, Devra Ehrlich, Margot Grieser, Jennifer Winston, Jenessa Lombardi, Dusty Gibson, Stormy Saif, Linda Killian, Mary L. Lantz, Kristina Tell, Rachel Torchetti, Mia Robbe-Austerman, Suelee Nelson, Martha I. Faith, Seth A. Bowman, Andrew S. SARS-CoV-2 infection in free-ranging white-tailed deer (Odocoileus virginianus) |
title | SARS-CoV-2 infection in free-ranging white-tailed deer (Odocoileus virginianus) |
title_full | SARS-CoV-2 infection in free-ranging white-tailed deer (Odocoileus virginianus) |
title_fullStr | SARS-CoV-2 infection in free-ranging white-tailed deer (Odocoileus virginianus) |
title_full_unstemmed | SARS-CoV-2 infection in free-ranging white-tailed deer (Odocoileus virginianus) |
title_short | SARS-CoV-2 infection in free-ranging white-tailed deer (Odocoileus virginianus) |
title_sort | sars-cov-2 infection in free-ranging white-tailed deer (odocoileus virginianus) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597885/ https://www.ncbi.nlm.nih.gov/pubmed/34790982 http://dx.doi.org/10.1101/2021.11.04.467308 |
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