Patient similarity network of newly diagnosed multiple myeloma identifies patient subgroups with distinct genetic features and clinical implications

The remarkable genetic heterogeneity of multiple myeloma poses a substantial challenge for proper prognostication and clinical management of patients. Here, we introduce MM-PSN, the first multiomics patient similarity network of myeloma. MM-PSN enabled accurate dissection of the genetic and molecula...

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Detalles Bibliográficos
Autores principales: Bhalla, Sherry, Melnekoff, David T., Aleman, Adolfo, Leshchenko, Violetta, Restrepo, Paula, Keats, Jonathan, Onel, Kenan, Sawyer, Jeffrey R., Madduri, Deepu, Richter, Joshua, Richard, Shambavi, Chari, Ajai, Cho, Hearn Jay, Dudley, Joel T., Jagannath, Sundar, Laganà, Alessandro, Parekh, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598000/
https://www.ncbi.nlm.nih.gov/pubmed/34788103
http://dx.doi.org/10.1126/sciadv.abg9551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598000/
https://www.ncbi.nlm.nih.gov/pubmed/34788103
http://dx.doi.org/10.1126/sciadv.abg9551

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