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Patient similarity network of newly diagnosed multiple myeloma identifies patient subgroups with distinct genetic features and clinical implications
The remarkable genetic heterogeneity of multiple myeloma poses a substantial challenge for proper prognostication and clinical management of patients. Here, we introduce MM-PSN, the first multiomics patient similarity network of myeloma. MM-PSN enabled accurate dissection of the genetic and molecula...
Autores principales: | Bhalla, Sherry, Melnekoff, David T., Aleman, Adolfo, Leshchenko, Violetta, Restrepo, Paula, Keats, Jonathan, Onel, Kenan, Sawyer, Jeffrey R., Madduri, Deepu, Richter, Joshua, Richard, Shambavi, Chari, Ajai, Cho, Hearn Jay, Dudley, Joel T., Jagannath, Sundar, Laganà, Alessandro, Parekh, Samir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598000/ https://www.ncbi.nlm.nih.gov/pubmed/34788103 http://dx.doi.org/10.1126/sciadv.abg9551 |
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