Breadth of CD8 T-cell mediated inhibition of replication of diverse HIV-1 transmitted-founder isolates correlates with the breadth of recognition within a comprehensive HIV-1 Gag, Nef, Env and Pol potential T-cell epitope (PTE) peptide set

Full characterisation of functional HIV-1-specific T-cell responses, including identification of recognised epitopes linked with functional antiviral responses, would aid development of effective vaccines but is hampered by HIV-1 sequence diversity. Typical approaches to identify T-cell epitopes uti...

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Detalles Bibliográficos
Autores principales: Hayes, Peter, Fernandez, Natalia, Ochsenbauer, Christina, Dalel, Jama, Hare, Jonathan, King, Deborah, Black, Lucas, Streatfield, Claire, Kakarla, Vanaja, Macharia, Gladys, Makinde, Julia, Price, Matt, Hunter, Eric, Gilmour, Jill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598018/
https://www.ncbi.nlm.nih.gov/pubmed/34788349
http://dx.doi.org/10.1371/journal.pone.0260118

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