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Signature required: The transcriptional response to tuberculosis

The majority of humans infected with Mycobacterium tuberculosis never experience clinical symptoms or signs, but predicting those who will remains out of reach. Here, we discuss recent studies that reveal patterns and pathways that determine who is at highest risk for progression.

Detalles Bibliográficos
Autores principales: Barry, Clifton E., Mayer-Barber, Katrin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598054/
https://www.ncbi.nlm.nih.gov/pubmed/34779817
http://dx.doi.org/10.1084/jem.20211665
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author Barry, Clifton E.
Mayer-Barber, Katrin D.
author_facet Barry, Clifton E.
Mayer-Barber, Katrin D.
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description The majority of humans infected with Mycobacterium tuberculosis never experience clinical symptoms or signs, but predicting those who will remains out of reach. Here, we discuss recent studies that reveal patterns and pathways that determine who is at highest risk for progression.
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spelling pubmed-85980542022-06-06 Signature required: The transcriptional response to tuberculosis Barry, Clifton E. Mayer-Barber, Katrin D. J Exp Med Viewpoint The majority of humans infected with Mycobacterium tuberculosis never experience clinical symptoms or signs, but predicting those who will remains out of reach. Here, we discuss recent studies that reveal patterns and pathways that determine who is at highest risk for progression. Rockefeller University Press 2021-11-15 /pmc/articles/PMC8598054/ /pubmed/34779817 http://dx.doi.org/10.1084/jem.20211665 Text en This is a work of the U.S. Government and is not subject to copyright protection in the United States. Foreign copyrights may apply. https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Viewpoint
Barry, Clifton E.
Mayer-Barber, Katrin D.
Signature required: The transcriptional response to tuberculosis
title Signature required: The transcriptional response to tuberculosis
title_full Signature required: The transcriptional response to tuberculosis
title_fullStr Signature required: The transcriptional response to tuberculosis
title_full_unstemmed Signature required: The transcriptional response to tuberculosis
title_short Signature required: The transcriptional response to tuberculosis
title_sort signature required: the transcriptional response to tuberculosis
topic Viewpoint
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598054/
https://www.ncbi.nlm.nih.gov/pubmed/34779817
http://dx.doi.org/10.1084/jem.20211665
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