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Time‐resolved dosimetry with pencil‐beam scanning for quality assurance/quality control in particle therapy

This study aimed to measure dose in a scanning carbon beam‐irradiation field with high sampling rate that is sufficient for identifying spots and verifying the characteristics of the scanning beam that cannot generally be derived from the dose. To identify the spot, which is the smallest control uni...

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Autores principales: Han, Soorim, Furukawa, Takuji, Hara, Yousuke, Fukuda, Shigekazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598136/
https://www.ncbi.nlm.nih.gov/pubmed/34664386
http://dx.doi.org/10.1002/acm2.13397
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author Han, Soorim
Furukawa, Takuji
Hara, Yousuke
Fukuda, Shigekazu
author_facet Han, Soorim
Furukawa, Takuji
Hara, Yousuke
Fukuda, Shigekazu
author_sort Han, Soorim
collection PubMed
description This study aimed to measure dose in a scanning carbon beam‐irradiation field with high sampling rate that is sufficient for identifying spots and verifying the characteristics of the scanning beam that cannot generally be derived from the dose. To identify the spot, which is the smallest control unit of beam information during irradiation, effecting measurements with a sampling time of 10 μs or shorter is necessary. The provided dose within a specific time is referred to as time‐resolved dose (TRD). We designed a circuit for time‐resolved dosimetry using a fast‐data acquisition unit (SL1000, Yokogawa Electric Co.), which can measure 100 000 samples per second. Moreover, we used converters to enable a connection between an ionization chamber (IC) and the SL1000. TRD was measured successfully using point irradiation and two‐dimensional irradiation patterns in a scanned carbon beam. Based on the moving time of the spot obtained from the position monitor, the dose delivered to the IC from each spot position (spot dose) was interpreted. The spot dose, displacement of the chamber from the beam's center axis, and beam size were derived using TRD and position monitor outputs, which were measured concurrent with TRD. Spot dose up to a radius of 8 mm area from the IC's center were observed. Using the spot‐dose equations and simulation, we show that the spot dose of each position varies depending on the beam size and displacement of the IC's center from the beam's center axis. We devise an interpretation method for the characteristics that may apply to quality assurance, such as the verification of the trend for the beam axis and isocenter to coincide, as well as beam‐size verification.
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spelling pubmed-85981362021-12-02 Time‐resolved dosimetry with pencil‐beam scanning for quality assurance/quality control in particle therapy Han, Soorim Furukawa, Takuji Hara, Yousuke Fukuda, Shigekazu J Appl Clin Med Phys Radiation Oncology Physics This study aimed to measure dose in a scanning carbon beam‐irradiation field with high sampling rate that is sufficient for identifying spots and verifying the characteristics of the scanning beam that cannot generally be derived from the dose. To identify the spot, which is the smallest control unit of beam information during irradiation, effecting measurements with a sampling time of 10 μs or shorter is necessary. The provided dose within a specific time is referred to as time‐resolved dose (TRD). We designed a circuit for time‐resolved dosimetry using a fast‐data acquisition unit (SL1000, Yokogawa Electric Co.), which can measure 100 000 samples per second. Moreover, we used converters to enable a connection between an ionization chamber (IC) and the SL1000. TRD was measured successfully using point irradiation and two‐dimensional irradiation patterns in a scanned carbon beam. Based on the moving time of the spot obtained from the position monitor, the dose delivered to the IC from each spot position (spot dose) was interpreted. The spot dose, displacement of the chamber from the beam's center axis, and beam size were derived using TRD and position monitor outputs, which were measured concurrent with TRD. Spot dose up to a radius of 8 mm area from the IC's center were observed. Using the spot‐dose equations and simulation, we show that the spot dose of each position varies depending on the beam size and displacement of the IC's center from the beam's center axis. We devise an interpretation method for the characteristics that may apply to quality assurance, such as the verification of the trend for the beam axis and isocenter to coincide, as well as beam‐size verification. John Wiley and Sons Inc. 2021-10-19 /pmc/articles/PMC8598136/ /pubmed/34664386 http://dx.doi.org/10.1002/acm2.13397 Text en © 2021 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Han, Soorim
Furukawa, Takuji
Hara, Yousuke
Fukuda, Shigekazu
Time‐resolved dosimetry with pencil‐beam scanning for quality assurance/quality control in particle therapy
title Time‐resolved dosimetry with pencil‐beam scanning for quality assurance/quality control in particle therapy
title_full Time‐resolved dosimetry with pencil‐beam scanning for quality assurance/quality control in particle therapy
title_fullStr Time‐resolved dosimetry with pencil‐beam scanning for quality assurance/quality control in particle therapy
title_full_unstemmed Time‐resolved dosimetry with pencil‐beam scanning for quality assurance/quality control in particle therapy
title_short Time‐resolved dosimetry with pencil‐beam scanning for quality assurance/quality control in particle therapy
title_sort time‐resolved dosimetry with pencil‐beam scanning for quality assurance/quality control in particle therapy
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598136/
https://www.ncbi.nlm.nih.gov/pubmed/34664386
http://dx.doi.org/10.1002/acm2.13397
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