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Validation of spline modeling for calculation of electron insert factors for varian linear accelerators

There are several methods available in the literature for predicting the insert factor for clinical electron beams. The purpose of this work was to build on a previously published technique that uses a bivariate spline model generated from elliptically parameterized empirical measurements. The techn...

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Autores principales: Baltz, Garrett C., Kirsner, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598145/
https://www.ncbi.nlm.nih.gov/pubmed/34609063
http://dx.doi.org/10.1002/acm2.13430
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author Baltz, Garrett C.
Kirsner, Steven M.
author_facet Baltz, Garrett C.
Kirsner, Steven M.
author_sort Baltz, Garrett C.
collection PubMed
description There are several methods available in the literature for predicting the insert factor for clinical electron beams. The purpose of this work was to build on a previously published technique that uses a bivariate spline model generated from elliptically parameterized empirical measurements. The technique has been previously validated for Elekta linear accelerators for limited clinical electron setups. The same model is applied to Varian machines to test its efficacy for use with these linear accelerators. Insert factors for specifically designed elliptical cutouts were measured to create spline models for 6, 9, 12, 16, and 20 MeV electron energies for four different cone sizes at source‐to‐surface distances (SSD) of 100, 105, and 110 cm. Insert factor validation measurements of patient cutouts and clinical standard cutouts were acquired to compare to model predictions. Agreement between predicted insert factors and validation measurements averaged 0.8% over all energies, cones, and clinical SSDs, with an uncertainty of 0.6% (1SD), and maximum deviation of 2.1%. The model demonstrated accurate predictions of insert factors using the minimum required amount of input data for small cones, with more input measurements required for larger cones. The results of this study provide expanded validation of this technique to predict insert factors for all energies, cones, and SSDs that would be used in most clinical situations. This level of accuracy and the ease of creating the model necessary for the insert factor predictions demonstrate its acceptability to use clinically for Varian machines.
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spelling pubmed-85981452021-12-02 Validation of spline modeling for calculation of electron insert factors for varian linear accelerators Baltz, Garrett C. Kirsner, Steven M. J Appl Clin Med Phys Radiation Oncology Physics There are several methods available in the literature for predicting the insert factor for clinical electron beams. The purpose of this work was to build on a previously published technique that uses a bivariate spline model generated from elliptically parameterized empirical measurements. The technique has been previously validated for Elekta linear accelerators for limited clinical electron setups. The same model is applied to Varian machines to test its efficacy for use with these linear accelerators. Insert factors for specifically designed elliptical cutouts were measured to create spline models for 6, 9, 12, 16, and 20 MeV electron energies for four different cone sizes at source‐to‐surface distances (SSD) of 100, 105, and 110 cm. Insert factor validation measurements of patient cutouts and clinical standard cutouts were acquired to compare to model predictions. Agreement between predicted insert factors and validation measurements averaged 0.8% over all energies, cones, and clinical SSDs, with an uncertainty of 0.6% (1SD), and maximum deviation of 2.1%. The model demonstrated accurate predictions of insert factors using the minimum required amount of input data for small cones, with more input measurements required for larger cones. The results of this study provide expanded validation of this technique to predict insert factors for all energies, cones, and SSDs that would be used in most clinical situations. This level of accuracy and the ease of creating the model necessary for the insert factor predictions demonstrate its acceptability to use clinically for Varian machines. John Wiley and Sons Inc. 2021-10-05 /pmc/articles/PMC8598145/ /pubmed/34609063 http://dx.doi.org/10.1002/acm2.13430 Text en © 2021 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Baltz, Garrett C.
Kirsner, Steven M.
Validation of spline modeling for calculation of electron insert factors for varian linear accelerators
title Validation of spline modeling for calculation of electron insert factors for varian linear accelerators
title_full Validation of spline modeling for calculation of electron insert factors for varian linear accelerators
title_fullStr Validation of spline modeling for calculation of electron insert factors for varian linear accelerators
title_full_unstemmed Validation of spline modeling for calculation of electron insert factors for varian linear accelerators
title_short Validation of spline modeling for calculation of electron insert factors for varian linear accelerators
title_sort validation of spline modeling for calculation of electron insert factors for varian linear accelerators
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598145/
https://www.ncbi.nlm.nih.gov/pubmed/34609063
http://dx.doi.org/10.1002/acm2.13430
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