Local chromatin fiber folding represses transcription and loop extrusion in quiescent cells

A longstanding hypothesis is that chromatin fiber folding mediated by interactions between nearby nucleosomes represses transcription. However, it has been difficult to determine the relationship between local chromatin fiber compaction and transcription in cells. Further, global changes in fiber di...

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Detalles Bibliográficos
Autores principales: Swygert, Sarah G, Lin, Dejun, Portillo-Ledesma, Stephanie, Lin, Po-Yen, Hunt, Dakota R, Kao, Cheng-Fu, Schlick, Tamar, Noble, William S, Tsukiyama, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598167/
https://www.ncbi.nlm.nih.gov/pubmed/34734806
http://dx.doi.org/10.7554/eLife.72062

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