High unbound flucloxacillin fraction in critically ill patients

OBJECTIVES: To describe the unbound and total flucloxacillin pharmacokinetics in critically ill patients and to define optimal dosing strategies. PATIENTS AND METHODS: Observational multicentre study including a total of 33 adult ICU patients receiving flucloxacillin, given as intermittent or contin...

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Detalles Bibliográficos
Autores principales: Wallenburg, Eveline, ter Heine, Rob, de Lange, Dylan W, van Leeuwen, Henk, Schouten, Jeroen A, ten Oever, Jaap, Kolwijck, Eva, Burger, David M, Pickkers, Peter, Gieling, Emilie M, de Maat, Monique M, Frenzel, Tim, Brüggemann, Roger J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598283/
https://www.ncbi.nlm.nih.gov/pubmed/34463730
http://dx.doi.org/10.1093/jac/dkab314

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