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An Experimental Study: Benefits of Digoxin on Hepatotoxicity Induced by Methotrexate Treatment
PURPOSE: The aim of the study is to examine the possible therapeutic effects of a known cardiac glycoside, digoxin, on a rat model of MTX-induced hepatotoxicity. METHODS: The study was conducted on twenty-four male rats. While eighteen rats received a single dose of 20 mg/kg MTX to obtain an injured...
Autores principales: | Taskin, Banu, Erdoğan, Mümin Alper, Yiğittürk, Gürkan, Alper, Sibel, Erbaş, Oytun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598353/ https://www.ncbi.nlm.nih.gov/pubmed/34804155 http://dx.doi.org/10.1155/2021/6619844 |
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