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Acute and sublethal intoxication of malathion in an Indian major carp, Labeo rohita: haematological and biochemical responses

This study aimed to determine the median lethal concentration (96-h LC(50)), acute and sublethal effects of malathion, an organophosphorus pesticide on hematological and biochemical responses in an Indian major carp, Labeo rohita. In this study, the LC(50) value of malathion for 96 h was found to be...

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Autores principales: Sivanandan, Juginu Mankuzhiyil, Binukumari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Environmental Health and Toxicology/Korea Society for Environmental Analysis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598410/
https://www.ncbi.nlm.nih.gov/pubmed/34784659
http://dx.doi.org/10.5620/eaht.2021016
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author Sivanandan, Juginu Mankuzhiyil
Binukumari,
author_facet Sivanandan, Juginu Mankuzhiyil
Binukumari,
author_sort Sivanandan, Juginu Mankuzhiyil
collection PubMed
description This study aimed to determine the median lethal concentration (96-h LC(50)), acute and sublethal effects of malathion, an organophosphorus pesticide on hematological and biochemical responses in an Indian major carp, Labeo rohita. In this study, the LC(50) value of malathion for 96 h was found to be 3.4 ppm. During acute (3.4 ppm) and sublethal [1/10th of 96 h LC(50) value (0.34 ppm) studies, all the hematological parameters except WBC were significantly decreased (p<0.05). Besides, when compared with the control group, a significant (p<0.05) decrease in biochemical activity was also observed in malathion treated fish during acute and sublethal exposure periods. These results suggest that the tested concentrations of malathion could have significant adverse effects on the hematological and biochemical parameters of fish, Labeo rohita. The changes in the parameters can be effectively used to determine the impact of malathion in the aquatic ecosystem.
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spelling pubmed-85984102021-12-01 Acute and sublethal intoxication of malathion in an Indian major carp, Labeo rohita: haematological and biochemical responses Sivanandan, Juginu Mankuzhiyil Binukumari, Environ Anal Health Toxicol Original Article This study aimed to determine the median lethal concentration (96-h LC(50)), acute and sublethal effects of malathion, an organophosphorus pesticide on hematological and biochemical responses in an Indian major carp, Labeo rohita. In this study, the LC(50) value of malathion for 96 h was found to be 3.4 ppm. During acute (3.4 ppm) and sublethal [1/10th of 96 h LC(50) value (0.34 ppm) studies, all the hematological parameters except WBC were significantly decreased (p<0.05). Besides, when compared with the control group, a significant (p<0.05) decrease in biochemical activity was also observed in malathion treated fish during acute and sublethal exposure periods. These results suggest that the tested concentrations of malathion could have significant adverse effects on the hematological and biochemical parameters of fish, Labeo rohita. The changes in the parameters can be effectively used to determine the impact of malathion in the aquatic ecosystem. Korean Society of Environmental Health and Toxicology/Korea Society for Environmental Analysis 2021-09-27 /pmc/articles/PMC8598410/ /pubmed/34784659 http://dx.doi.org/10.5620/eaht.2021016 Text en Copyright © 2021 The Korean Society of Environmental Health and Toxicology/Korea Society for Environmental Analysis https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Sivanandan, Juginu Mankuzhiyil
Binukumari,
Acute and sublethal intoxication of malathion in an Indian major carp, Labeo rohita: haematological and biochemical responses
title Acute and sublethal intoxication of malathion in an Indian major carp, Labeo rohita: haematological and biochemical responses
title_full Acute and sublethal intoxication of malathion in an Indian major carp, Labeo rohita: haematological and biochemical responses
title_fullStr Acute and sublethal intoxication of malathion in an Indian major carp, Labeo rohita: haematological and biochemical responses
title_full_unstemmed Acute and sublethal intoxication of malathion in an Indian major carp, Labeo rohita: haematological and biochemical responses
title_short Acute and sublethal intoxication of malathion in an Indian major carp, Labeo rohita: haematological and biochemical responses
title_sort acute and sublethal intoxication of malathion in an indian major carp, labeo rohita: haematological and biochemical responses
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598410/
https://www.ncbi.nlm.nih.gov/pubmed/34784659
http://dx.doi.org/10.5620/eaht.2021016
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