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Consensus evidence-based clinical practice guidelines for the diagnosis and treat-to-target management of osteoporosis in Africa: an initiative by the African Society of Bone Health and Metabolic Bone Diseases

SUMMARY: The objective of this consensus statement is to inform the clinical practice communities, research centres and policymakers across Africa of the results of the recommendations for osteoporosis prevention, diagnosis and management. The developed guideline provides state-of-the-art informatio...

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Autores principales: El Miedany, Y, Paruk, Farhanah, Kalla, Asgar, Adebajo, A., El Gaafary, Maha, El Maghraoui, Abdellah, Ngandeu, Madeleine, Dey, Dzifa, Gadallah, Naglaa, Elwy, Mohamed, Moosajee, Farzana, Abu-Zaid, Mohammed Hassan, Galal, Salwa, Miladi, Soussen, Hassan, Waleed, Fadlelmola, Abubaker, Saber, Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598938/
https://www.ncbi.nlm.nih.gov/pubmed/34792646
http://dx.doi.org/10.1007/s11657-021-01035-z
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author El Miedany, Y
Paruk, Farhanah
Kalla, Asgar
Adebajo, A.
El Gaafary, Maha
El Maghraoui, Abdellah
Ngandeu, Madeleine
Dey, Dzifa
Gadallah, Naglaa
Elwy, Mohamed
Moosajee, Farzana
Abu-Zaid, Mohammed Hassan
Galal, Salwa
Miladi, Soussen
Hassan, Waleed
Fadlelmola, Abubaker
Saber, Sally
author_facet El Miedany, Y
Paruk, Farhanah
Kalla, Asgar
Adebajo, A.
El Gaafary, Maha
El Maghraoui, Abdellah
Ngandeu, Madeleine
Dey, Dzifa
Gadallah, Naglaa
Elwy, Mohamed
Moosajee, Farzana
Abu-Zaid, Mohammed Hassan
Galal, Salwa
Miladi, Soussen
Hassan, Waleed
Fadlelmola, Abubaker
Saber, Sally
author_sort El Miedany, Y
collection PubMed
description SUMMARY: The objective of this consensus statement is to inform the clinical practice communities, research centres and policymakers across Africa of the results of the recommendations for osteoporosis prevention, diagnosis and management. The developed guideline provides state-of-the-art information and presents the conclusions and recommendations of the consensus panel regarding these issues. PURPOSE: To reach an African expert consensus on a treat-to-target strategy, based on current evidence for best practice, for the management of osteoporosis and prevention of fractures. METHOD: A 3-round Delphi process was conducted with 17 osteoporosis experts from different African countries. All rounds were conducted online. In round 1, experts reviewed a list of 21 key clinical questions. In rounds 2 and 3, they rated the statements stratified under each domain for its fit (on a scale of 1–9). After each round, statements were retired, modified or added in view of the experts’ suggestions and the percent agreement was calculated. Statements receiving rates of 7–9 by more than 75% of experts’ votes were considered as achieving consensus. RESULTS: The developed guidelines adopted a fracture risk-centric approach. Results of round 1 revealed that of the 21 proposed domains, 10 were accepted whereas 11 were amended. In round 2, 32 statements were presented: 2 statements were retired for similarity, 9 statements reached consensus, whereas modifications were suggested for 21 statements. After the 3rd round of rating, the experts came to consensus on the 32 statements. Frequency of high-rate recommendation ranged from 83.33 to 100%. The response rate of the experts was 100%. An algorithm for the osteoporosis management osteoporosis was suggested. CONCLUSION: This study is an important step in setting up a standardised osteoporosis service across the continent. Building a single model that can be applied in standard practice across Africa will enable the clinicians to face the key challenges of managing osteoporosis; furthermore, it highlights the unmet needs for the policymakers responsible for providing bone health care together with and positive outcomes of patients’ care.
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spelling pubmed-85989382021-11-18 Consensus evidence-based clinical practice guidelines for the diagnosis and treat-to-target management of osteoporosis in Africa: an initiative by the African Society of Bone Health and Metabolic Bone Diseases El Miedany, Y Paruk, Farhanah Kalla, Asgar Adebajo, A. El Gaafary, Maha El Maghraoui, Abdellah Ngandeu, Madeleine Dey, Dzifa Gadallah, Naglaa Elwy, Mohamed Moosajee, Farzana Abu-Zaid, Mohammed Hassan Galal, Salwa Miladi, Soussen Hassan, Waleed Fadlelmola, Abubaker Saber, Sally Arch Osteoporos Original Article SUMMARY: The objective of this consensus statement is to inform the clinical practice communities, research centres and policymakers across Africa of the results of the recommendations for osteoporosis prevention, diagnosis and management. The developed guideline provides state-of-the-art information and presents the conclusions and recommendations of the consensus panel regarding these issues. PURPOSE: To reach an African expert consensus on a treat-to-target strategy, based on current evidence for best practice, for the management of osteoporosis and prevention of fractures. METHOD: A 3-round Delphi process was conducted with 17 osteoporosis experts from different African countries. All rounds were conducted online. In round 1, experts reviewed a list of 21 key clinical questions. In rounds 2 and 3, they rated the statements stratified under each domain for its fit (on a scale of 1–9). After each round, statements were retired, modified or added in view of the experts’ suggestions and the percent agreement was calculated. Statements receiving rates of 7–9 by more than 75% of experts’ votes were considered as achieving consensus. RESULTS: The developed guidelines adopted a fracture risk-centric approach. Results of round 1 revealed that of the 21 proposed domains, 10 were accepted whereas 11 were amended. In round 2, 32 statements were presented: 2 statements were retired for similarity, 9 statements reached consensus, whereas modifications were suggested for 21 statements. After the 3rd round of rating, the experts came to consensus on the 32 statements. Frequency of high-rate recommendation ranged from 83.33 to 100%. The response rate of the experts was 100%. An algorithm for the osteoporosis management osteoporosis was suggested. CONCLUSION: This study is an important step in setting up a standardised osteoporosis service across the continent. Building a single model that can be applied in standard practice across Africa will enable the clinicians to face the key challenges of managing osteoporosis; furthermore, it highlights the unmet needs for the policymakers responsible for providing bone health care together with and positive outcomes of patients’ care. Springer London 2021-11-18 2021 /pmc/articles/PMC8598938/ /pubmed/34792646 http://dx.doi.org/10.1007/s11657-021-01035-z Text en © International Osteoporosis Foundation and National Osteoporosis Foundation 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Article
El Miedany, Y
Paruk, Farhanah
Kalla, Asgar
Adebajo, A.
El Gaafary, Maha
El Maghraoui, Abdellah
Ngandeu, Madeleine
Dey, Dzifa
Gadallah, Naglaa
Elwy, Mohamed
Moosajee, Farzana
Abu-Zaid, Mohammed Hassan
Galal, Salwa
Miladi, Soussen
Hassan, Waleed
Fadlelmola, Abubaker
Saber, Sally
Consensus evidence-based clinical practice guidelines for the diagnosis and treat-to-target management of osteoporosis in Africa: an initiative by the African Society of Bone Health and Metabolic Bone Diseases
title Consensus evidence-based clinical practice guidelines for the diagnosis and treat-to-target management of osteoporosis in Africa: an initiative by the African Society of Bone Health and Metabolic Bone Diseases
title_full Consensus evidence-based clinical practice guidelines for the diagnosis and treat-to-target management of osteoporosis in Africa: an initiative by the African Society of Bone Health and Metabolic Bone Diseases
title_fullStr Consensus evidence-based clinical practice guidelines for the diagnosis and treat-to-target management of osteoporosis in Africa: an initiative by the African Society of Bone Health and Metabolic Bone Diseases
title_full_unstemmed Consensus evidence-based clinical practice guidelines for the diagnosis and treat-to-target management of osteoporosis in Africa: an initiative by the African Society of Bone Health and Metabolic Bone Diseases
title_short Consensus evidence-based clinical practice guidelines for the diagnosis and treat-to-target management of osteoporosis in Africa: an initiative by the African Society of Bone Health and Metabolic Bone Diseases
title_sort consensus evidence-based clinical practice guidelines for the diagnosis and treat-to-target management of osteoporosis in africa: an initiative by the african society of bone health and metabolic bone diseases
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598938/
https://www.ncbi.nlm.nih.gov/pubmed/34792646
http://dx.doi.org/10.1007/s11657-021-01035-z
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