Reduced antibody activity against SARS-CoV-2 B.1.617.2 delta virus in serum of mRNA-vaccinated individuals receiving tumor necrosis factor-α inhibitors

BACKGROUND: Although vaccines effectively prevent coronavirus disease 2019 (COVID-19) in healthy individuals, they appear to be less immunogenic in individuals with chronic inflammatory disease (CID) or receiving chronic immunosuppression therapy. METHODS: Here we assessed a cohort of 77 individuals...

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Detalles Bibliográficos
Autores principales: Chen, Rita E., Gorman, Matthew J., Zhu, Daniel Y., Carreño, Juan Manuel, Yuan, Dansu, VanBlargan, Laura A., Burdess, Samantha, Lauffenburger, Douglas A., Kim, Wooseob, Turner, Jackson S., Droit, Lindsay, Handley, Scott A., Chahin, Salim, Deepak, Parakkal, O’Halloran, Jane A., Paley, Michael A., Presti, Rachel M., Wu, Gregory F., Krammer, Florian, Alter, Galit, Ellebedy, Ali H., Kim, Alfred H.J., Diamond, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Clinical and Translational Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599018/
https://www.ncbi.nlm.nih.gov/pubmed/34812429
http://dx.doi.org/10.1016/j.medj.2021.11.004

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